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BioWorld - Saturday, September 23, 2023
Home » Topics » Deals and M&A

Deals and M&A
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Deal illustration

Imugene in-licenses Precision Bioscience’s allogeneic CD19 CAR T in $227M deal

Aug. 16, 2023
By Tamra Sami
No Comments
Immuno-oncology company Imugene Ltd. has acquired a worldwide exclusive license to Precision Biosciences Inc.’s allogeneic CD19 CAR T-cell therapy program in a deal worth more than $227 million. The off-the-shelf CD19 CAR T-cell therapy, azercabtagene zapreleucel (azer-cel), could potentially be the first allogeneic CAR T to be approved, Imugene CEO Leslie Chong told BioWorld.
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Handshake with DNA, molecules
Immuno-oncology

Cytomed signs MOU to leverage CNK's Piggybac technology to permanently graft CARs into γδ T cells

Aug. 16, 2023
No Comments
Cytomed Therapeutics Ltd. has signed a memorandum of understanding (MOU) with Hangzhou CNK Therapeutics Co. Ltd. allowing Cytomed to utilize CNK's Piggybac technology to permanently graft the chimeric antigen receptor (CAR) gene into its γδ T cells via a non-viral gene editing method.
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Concept of business partnership
Biopharma deals July 2023

First seven months of 2023 sees $105.4B in biopharma deals and $37.6B in M&As

Aug. 15, 2023
By Amanda Lanier
No Comments
The June dip in biopharma deal value was short-lived, with July seeing 106 deals worth $17.57 billion, up 72.03% from $10.22 billion in July 2022.
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Astellas returns two gene therapies to Modalis

Aug. 15, 2023
By Marian (YoonJee) Chu
No Comments
Modalis Therapeutics Corp. – previously Edigene Corp. – has regained full rights to two gene therapy candidates for muscle disorders, MDL-201 and MDL-202, that were co-developed with Astellas Pharmaceutical Inc. since 2019.
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Green arrow up red arrow down

Med-tech deals reach $8.63B and M&As total $37.33B in first 7 months of 2023

Aug. 14, 2023
By Amanda Lanier
No Comments
Med-tech deal values the first seven months of the year are up more than 50% from last year. Meanwhile, M&As decreased almost 70% from the same time period in 2022.
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Zynerba finds Harmony in FXS takeover to the tune of $200M

Aug. 14, 2023
By Randy Osborne
No Comments
Harmony Biosciences Holdings Inc.’s agreement to acquire Zynerba Pharmaceuticals Inc. for $60 million cash plus as much as $140 million in contingent value rights (CVRs) didn’t register as one of the larger potential outlays recently, but Wall Street had questions about the term sheet just the same. Plymouth Meeting, Pa.-based Harmony is paying about $1.10 per share in cash for Zynerba, of Devon, Pa., plus one non-tradeable CVR tied to clinical, regulatory and sales milestones.
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Concept of business partnership
Biopharma deals July 2023

First seven months of 2023 sees $105.4B in biopharma deals and $37.6B in M&As

Aug. 11, 2023
By Amanda Lanier
No Comments
The June dip in biopharma deal value was short-lived, with July seeing 106 deals worth $17.57 billion, up 72.03% from $10.22 billion in July 2022. In the first seven months of 2023, 778 deals were completed worth $105.39 billion, compared to 995 deals worth $105.9 billion in the same period last year, a decrease of 0.48% by value and a decrease of 21.8% by volume. The same timeframe in 2021 saw 1,240 deals valued at $107 billion, 1,228 deals worth $112.23 billion in 2020, and 963 deals totaling $93.39 billion in 2019.
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Acquisition target

Novo Nordisk targets CB1 for obesity with potential $1B+ buyout of Inversago

Aug. 10, 2023
By Karen Carey
No Comments
Building out its metabolic franchise, Novo Nordisk A/S is buying privately held Montreal-based Inversago Pharma Inc. for up to $1.075 billion, gaining lead asset INV-202, an oral cannabinoid 1 (CB1) inverse agonist. The candidate has demonstrated weight loss potential in a phase Ib trial and is currently in a phase II for diabetic kidney disease. Novo Nordisk’s interest in INV-202 is to explore its potential for obesity and obesity-related complications.
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Astellas returns two gene therapies to Modalis

Aug. 10, 2023
By Marian (YoonJee) Chu
No Comments
Modalis Therapeutics Corp. – previously Edigene Corp. – has regained full rights to two gene therapy candidates for muscle disorders, MDL-201 and MDL-202, that were co-developed with Astellas Pharmaceutical Inc. since 2019.
Read More
SK Biocience-Novavax signing agreement

Settling debt, strengthening ties: Novavax hands 6.45% stake to SK Bioscience

Aug. 9, 2023
By Marian (YoonJee) Chu
No Comments
Novavax Inc. has signed off 6.5 million shares to SK Bioscience Co. Ltd. for an $85 million equity investment from the South Korean pharmaceutical firm, which also wrote off some of Novavax’s manufacturing liabilities, as part of their continuing vaccine alliance. Seongnam-si, South Korea-based SK Bioscience purchased Novavax shares at $13 each, reflecting a 59% premium over the 90-day trading value, to gain a 6.45% stake in the Gaithersburg, Md.-based mRNA vaccine company, an SK Bioscience spokesperson confirmed to BioWorld.
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