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BioWorld - Friday, July 18, 2025
Home » Topics » Deals and M&A

Deals and M&A
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Handshake with cityscape and businesspeople

Robust deals hit $197B in 2020; M&As ready to rebound

Jan. 12, 2021
By Karen Carey
With several deals and M&As falling within the highest values on record, 2020 turned out to be a solid year for the biopharma industry. Expectations are optimistic moving into 2021, when the U.S. will welcome a new president and its citizens should reach herd immunity from COVID-19.
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Sanofi goes one step Biond checkpoint madness with $1B-plus cancer deal

Jan. 12, 2021
By Randy Osborne
Biond Biologics Ltd. co-founder and CEO Tehila Ben-Moshe told BioWorld that “a relatively small group of scientists who are very motivated started with a very basic scientific idea, which we were able to take all the way into clinical trials in four years,” and draw the interest of Paris-based Sanofi SA in a checkpoint inhibitor with multi-cell effects. In its second major deal of the week, Sanofi is pledging $125 million up front and more than $1 billion more in potential development, regulatory and sales-related milestone payments to Biond, of Misgav, Israel.
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Biotech deal illustration

Boehringer continues cancer investment in $1B deal with Enara

Jan. 12, 2021
By Lee Landenberger and Nuala Moran
LONDON – Enara Bio Ltd. has landed the first major deal around its dark antigen technology platform, signing up Boehringer Ingelheim GmbH in an agreement worth a potential €876 million (US$1.06 billion). Reaching that figure would require a product to make it to market. More immediately, Enara is getting an up-front payment, research and preclinical milestones for each of up to three tumor types explored in the partnership.
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Antibodies attacking cancer cell

Beigene inks $2.2B PD-1 deal with Novartis for cancer drug tislelizumab

Jan. 12, 2021
By Elise Mak
BEIJING – Beigene Ltd. out-licensed its anti-PD-1 monoclonal antibody tislelizumab to Novartis AG in a deal worth up to $2.2 billion, including $650 million up front. Novartis gains rights to develop and commercialize tislelizumab in the U.S., Canada, Mexico, the EU, the U.K., Norway, Switzerland, Iceland, Liechtenstein, Russia and Japan.
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Handshake with globe background and digital overlay

EY Report: Expect M&A to catch fire in 2021

Jan. 11, 2021
By Annette Boyle
While the first quarter may be a little slow as the winter COVID-19 surge continues to disrupt business, expect high capital reserves in med tech and life sciences to make 2021 a year for brisk deal activity, according to the 2021 Ernst & Young (EY) M&A Firepower report. In 2020, industry M&A activity fell to the lowest levels since 2014, but the multinational audit and consulting firm found that the industry now has record levels of deal capacity that it is poised to use to accelerate growth coming out of the pandemic.
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More than $1B in partnering deals keep last year’s momentum going

Jan. 11, 2021
By Lee Landenberger
As a virtual 39th J.P. Morgan Annual Healthcare Conference begins, typically one of the biggest events of the year, biopharma dealmaking barreled ahead with five new deals Jan. 11 that could eventually hit $1.04 billion in total.
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Eggs in two baskets with Bluebird split; ‘net positive’ to uncage value?

Jan. 11, 2021
By Randy Osborne
Bluebird Bio Inc. CEO Nick Leschly conceded that it’s “hard for folks on the outside looking in” to understand why the firm would cleave its severe genetic disease (SGD) and oncology efforts into two independently traded public companies, but said the Cambridge, Mass.-based firm is making the change by the end of this year in order “to make sure we can basically fall down and get back up and learn everything we can in the most disciplined manner,” he said.
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Antibodies

No IPO for Kymab as Sanofi offers $1.1B up front plus $350M in milestones

Jan. 11, 2021
By Cormac Sheridan
DUBLIN – Sanofi SA is paying $1.1 billion up front and up to $350 million more in potential clinical development and regulatory milestones to acquire antibody developer Kymab Ltd. The deal adds to Sanofi’s pipeline first-in-class OX40-ligand blocker KY-1005, which recently hit the primary endpoints of a phase IIa trial in atopic dermatitis, as well as a second clinical-stage asset, KY-1044, an ICOS agonist in development for solid tumors. It also brings Sanofi a new antibody discovery platform, comprising several transgenic mouse strains, which collectively encode all the building blocks required to produce fully human antibodies.
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Hands holding gears

Lilly looks to Blacksmith to Forge new metalloenzyme portfolio

Jan. 8, 2021
By Michael Fitzhugh
Forge Therapeutics Inc. spinout Blacksmith Medicines Inc. said Eli Lilly and Co. has committed up to $300 million in milestone payments to back its creation of five new immuno-oncology and inflammation-focused medicines targeting human metalloenzymes.
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Chimerix acquires Oncoceutics in a $78M stock/cash deal

Jan. 8, 2021
By Lee Landenberger
Chimerix Inc., which already has COVID-19 and smallpox therapeutics in clinical trials, has acquired privately held Oncoceutics Inc., bringing ONC-201, a small-molecule dopamine receptor D2 antagonist and caseinolytic protease agonist for treating recurrent gliomas harboring the H3 K27M mutation, into the fold.
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