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Home » Topics » Deals and M&A

Deals and M&A
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Scientists shaking hands in the lab
Drug design, drug delivery & technologies

With new leadership, Creyon enters a $1B-plus deal with Lilly

May 6, 2025
By Lee Landenberger
Less than a week after announcing it had a new CEO, privately held Creyon Bio Inc. began a licensing and research partnership with Eli Lilly and Co. Creyon is getting $13 million up front and could bring in more than $1 billion in milestone payments. The two plan to find, develop and commercialize RNA-targeted oligonucleotide treatments for a range of diseases.
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Conceptual 3D illustration showing degradation of motor neuron
Neurology/psychiatric

Alchemab and Lilly sign licensing agreement for ATLX-1282

May 6, 2025
No Comments
Alchemab Therapeutics Ltd. has entered into a licensing agreement with Eli Lilly and Co. for ATLX-1282, Alchemab’s first-in-class IND-ready program targeting a novel receptor and mechanism for amyotrophic lateral sclerosis (ALS) and other neurodegenerative conditions.
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Handshake with digital globe overlay

Med-tech financings and guidance strong despite tariffs

May 5, 2025
By Annette Boyle
April data and first quarter earnings reports show remarkable resilience in med tech, even as other sectors continue to suffer in response to tariffs and changing regulations. Not that tariffs proved insignificant: several companies reported annualized impacts north of half a billion dollars, but fundamentals and increased interest in med tech as a haven gave most players sufficient breathing room to absorb the impact with minimal adjustments.
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Kidneys

Dimerix strikes $601M Amicus deal for kidney disease drug DMX-200

May 1, 2025
By Tamra Sami
Dimerix Ltd. sealed an exclusive license agreement with Amicus Therapeutics Inc. for commercialization of its phase III kidney disease candidate, DMX-200, in a deal valued at AU$940 million (US$601.22 million).
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With new leadership, Creyon enters a $1B-plus deal with Lilly

May 1, 2025
By Lee Landenberger
Less than a week after announcing it had a new CEO, privately held Creyon Bio Inc. began a licensing and research partnership with Eli Lilly and Co. Creyon is getting $13 million up front and could bring in more than $1 billion in milestone payments. The two plan to find, develop and commercialize RNA-targeted oligonucleotide treatments for a range of diseases.
Read More
World globe, DNA sequencing illustration.
LSX World Congress

Emerging markets presents opportunities for med tech

April 30, 2025
By Shani Alexander
Med tech companies were reminded that there are opportunities in emerging and growing markets as they look for ways to adapt to the uncertainties created by the U.S. administration threats of import tariffs. With large populations, and relatively untapped markets, these opportunities represent new destinations for the med tech products. However, the U.S. cannot easily be replaced and there will be challenges in these markets, delegates heard at the LSX World Congress, in London.
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Regulus’ rare kidney disease drug draws Novartis in potential $1.7B buyout

April 30, 2025
By Jennifer Boggs
Regulus Therapeutics Inc. CEO Jay Hagan told investors in a January call the company had no interest in “simply out-licensing” rights to lead candidate farabursen, an oligonucleotide targeting autosomal dominant polycystic kidney disease set to start phase III testing on a path to a potential accelerated approval. And now, there’s no need to, as Regulus found a buyer for the whole company in a deal with Novartis AG valued at about $1.7 billion.
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Handshake, businessmen holding dollar sign, lightbulb
LSX World Congress

Startup, strategic relationship dependent on fair terms

April 29, 2025
By Shani Alexander
No Comments
Partnership agreements between startups and strategics need to be based on terms that are fair otherwise they will be rejected.
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China in red on globe
Chinabio 2025

US capital crunch pushes China biotechs to roundabout financings

April 29, 2025
By Marian (YoonJee) Chu
Tightening of U.S. regulation and capital is leading Chinese biotechs to alternative and new models of financing, ranging from cross-border licensing deals, M&As, the so-called newco model and overseas listings.
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Handshake with digital globe overlay

Chinabio 2025: Europe-China pharma deals rise as US markets shut

April 29, 2025
By Marian (YoonJee) Chu
Europe was a bigger counterpart to China in pharmaceutical dealmaking than the U.S. last year, speakers at Chinabio Partnering Forum said April 23, and the trend is likely to continue in 2025 with the shuttering of U.S. capital and volatility ailing global markets.
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