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Home » Topics » Deals and M&A

Deals and M&A
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Brain with handshake and cityscape

Vigil takeover brings TREM2 Alzheimer’s prospect to Sanofi

May 22, 2025
By Randy Osborne
No Comments
Sanofi SA made good on its plan to bear down on M&A by agreeing to buy Vigil Neuroscience Inc. for $8 per share (NASDAQ:VIGL). Included in the transaction is a non-tradeable contingent value right entitling the holder to potentially collect $2 per share more in cash, payable following the first commercial sale of the phase II-ready VG-3927, a small-molecule triggering receptor expressed on myeloid cells 2 (TREM2) antagonist for Alzheimer’s disease, if achieved within a specific period. Watertown, Mass.-based Vigil’s stock closed May 22 at $7.88, up $5.57, or 241%.
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Art concept for medical research

Like glue: Orionis and Genentech begin their second collaboration

May 21, 2025
By Lee Landenberger
No Comments
Orionis Biosciences Inc. is sticking with Genentech Inc. in a second deal to discover small-molecule monovalent glue therapies for treating cancer. Privately held Orionis is getting $105 million up front and could earn more than $2 billion in R&D, development, commercial and net sales milestones, plus royalties. The multiyear collaboration calls for Orionis to handle discovery and optimization of molecular glues, with Genentech in charge of later-stage preclinical and clinical development, regulatory filing and commercialization of any small molecules the partnership produces.
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Hands holding torn contract

Medtronic aims to sweeten appeal by unloading diabetes unit

May 21, 2025
By Annette Boyle
Medtronic plc revealed plans to spin off its underperforming diabetes unit as a separate public company during its fourth quarter 2025 earnings call May 21. The company expects to complete the separation within 18 months.
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Medtronic aims to sweeten appeal by unloading Diabetes unit

May 21, 2025
By Annette Boyle
Medtronic plc revealed plans to spin off its underperforming diabetes unit as a separate public company during its fourth quarter 2025 earnings call on May 21. The company expects to complete the separation within 18 months.
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Hand cupping ear to illustration hearing loss

Rznomics in $1.3B Lilly pact to make hearing loss RNA editor drug

May 20, 2025
By Marian (YoonJee) Chu
No Comments
Rznomics Inc. scored a potential ₩1.9 trillion (US$1.35 billion) global license option agreement with Eli Lilly and Co. to codevelop a novel RNA editing gene therapy to treat hereditary hearing loss.
Read More
3d rendering of bispecific antibodies

Pfizer bets $6B+ on 3Sbio’s bispecific PD-1/VEGF antibody

May 20, 2025
By Marian (YoonJee) Chu
No Comments
Pfizer Inc. is paying $1.25 billion up front and up to $4.8 billion in milestone payments to gain global, ex-China rights to SSGJ-707, a PD-1/VEGF bispecific antibody from 3Sbio Inc. that recently won China clearance for a phase III study in lung cancer as a potential first-line monotherapy. Announced after U.S. market hours May 19, the exclusive agreement for SSGJ-707 spells up to $6.15 billion combined for Shenyang, China-based 3Sbio, along with separate tiered double-digit royalty payments on sales of SSGJ-707, if approved.
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Financial chart, upward arrow

Protagenic and Phytanix merger prompts a stock surge

May 19, 2025
By Lee Landenberger
No Comments
The merger of Protagenic Therapeutics Inc. and Phytanix Bio Inc. combines two different approaches to treating obesity and metabolic issues. The all-stock deal will merge Protagenic’s peptide candidate in IND-enabling development for treating depression, anxiety, posttraumatic stress disorder and additional indications, along with Phytanix’s cannabinoid and cannabinoid-like molecules for bladder pain syndrome and treatment-resistant focal seizures.
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23andme saliva collection kit

Regeneron plans to buy 23andme from bankruptcy for $256M

May 19, 2025
By Brian Orelli
No Comments
Regeneron Pharmaceuticals Inc. was the successful bidder for 23andme Holding Co.’s personal genome service, total health and research services business lines, including its biobank and associated assets, in the bankruptcy auction to sell 23andme's assets.
Read More
Acquisition puzzle

Biomarin snags potential ‘first-in-disease’ ERT in $270M Inozyme buy

May 16, 2025
By Jennifer Boggs
No Comments
It’s been a big week for Inozyme Pharma Inc. On the heels of a promising interim readout for phase III-stage enzyme replacement therapy (ERT) candidate INZ-701 in ENPP1 deficiency, the firm agreed to be acquired by Biomarin Pharmaceuticals Inc. in a deal valued at about $270 million, putting the rare disease ERT in the hands of an experienced commercial team.
Read More
Hand cupping ear to illustration hearing loss

Rznomics in $1.3B Lilly pact to make hearing loss RNA editor drug

May 15, 2025
By Marian (YoonJee) Chu
No Comments
Rznomics Inc. scored a potential ₩1.9 trillion (US$1.35 billion) global license option agreement with Eli Lilly and Co. to codevelop a novel RNA editing gene therapy to treat hereditary hearing loss.
Read More
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