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BioWorld - Sunday, October 1, 2023
Home » Topics » Cancer, BioWorld Asia

Cancer, BioWorld Asia
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HKEX building

Akeso reaps $314M via largest IPO on HKEX this year, eyes PD-1-based bispecific

April 28, 2020
By Elise Mak
No Comments
BEIJING – Pre-revenue Chinese biotech Akeso Inc., of Zhongshan, Guangdong province, launched a high-profile IPO on April 24 in Hong Kong to reap HK$2.4 billion (US$314 million), even though the economy is taking a hard hit from the COVID-19 pandemic. The proceeds will help advance its PD-1/CTLA4 bispecific antibody for cervical cancer, aiming to be on the market by late 2021. Backed by Morgan Stanley and J.P. Morgan, the bispecific antibody specialist issued around 159.5 million shares at HK$16.18 per share, representing the top end of the indicative range. The IPO received an overwhelming response from retail investors, with shares significantly oversubscribed by 639.2 times.
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Australian flag on laptop screen with health professional

Australia’s Kazia reports strong overall survival benefit in phase II glioblastoma trial; raises AU$7.2M

April 14, 2020
By Tamra Sami
No Comments
PERTH, Australia – Sydney-based Kazia Therapeutics Ltd. reported interim data showing that lead candidate paxalisib (formerly GDC-0084) saw a positive overall survival signal in its phase II glioblastoma trial, and the company raised AU$7.2 million (US$4.4 million) days after the data were released.
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Hands holding test tubes at laptop

Zai Lab obtains greater China rights for Regeneron’s oncology candidate

April 14, 2020
By David Ho
No Comments
HONG KONG – China and U.S.-based Zai Lab Ltd. has signed on to develop and commercialize REGN-1979, a CD20xCD3 bispecific antibody from Regeneron Pharmaceuticals Inc., of Tarrytown, N.Y.
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Gold chain link engraved with "partnership"

I-Mab scores regional deal for two candidates; submits IND for COVID-19 candidate in U.S. and South Korea

April 7, 2020
By David Ho
No Comments
HONG KONG – China’s I-Mab Biopharma Co. Ltd. has entered a strategic partnership with Indonesia’s PT Kalbe Genexine Biologics (KG Bio). Through the deal, KG Bio will receive the right of first negotiation to commercialize two I-Mab-discovered candidates in the ASEAN and MENA regions as well as Sri Lanka.
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Innovent brings in Alector’s anti-SIRP-alpha antibody for China market

March 31, 2020
By Elise Mak
No Comments
BEIJING – Suzhou-based Innovent Biologics Inc. has inked a deal with Alector Inc. to obtain the rights of the U.S. biotech’s AL-008 to develop and commercialize it for oncology indications in China.
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Coins, stock chart illustration

China’s Abbisko rakes in $70M series C funding amid economic turbulence

March 31, 2020
By Gina Lee
No Comments
HONG KONG – Chinese biopharmaceutical company Abbisko Therapeutics Co. Ltd., of Shanghai, defied turbulent stock markets amid the COVID-19 pandemic to snag $70 million in its latest round of financing.
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IPO, coins, financial chart

Innocare launches $288M IPO on HKEX, aims to advance BTK inhibitor

March 24, 2020
By Elise Mak
No Comments
BEIJING – Cancer and autoimmune specialist Innocare Pharma Ltd., of Beijing, made a strong debut to raise $288 million on the Hong Kong Stock Exchange (HKEX) on March 23, marking the second biggest IPO in the city since the beginning of this year.
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Harbour, Mount Sinai partner to develop Mabs targeting cancer, immunology and coronavirus

March 10, 2020
By David Ho
No Comments
HONG KONG – U.S., China and the Netherlands-based Harbour Biomed Therapeutics Ltd. has teamed up with Mount Sinai Health System, New York City's largest academic medical system, to develop novel biotherapies in oncology and immunology. The two parties will also be using Harbour’s H2L2 Harbour Mice platform to develop a monoclonal antibody (MAb) against the coronavirus that has turned into a global epidemic.
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Immutep reports positive interim phase II results in Keytruda combo basket trial

March 3, 2020
By Tamra Sami
No Comments
PERTH, Australia – Immutep Ltd. reported positive interim data for its phase II basket trial in non-small-cell lung cancer and head and neck squamous cell carcinoma for its lead immunotherapy in combination with Merck & Co. Inc.’s Keytruda (pembrolizumab).
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Singapore’s Tessa gains U.S. RMAT designation for CD30 CAR T, expands manufacturing efforts

March 3, 2020
By David Ho
No Comments
HONG KONG – Tessa Therapeutics Pte Ltd.’s CD30 CAR T-cell therapy has been granted a regenerative medicine advanced therapy designation by the U.S. FDA based on data from two independent phase I/II trials.
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