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BioWorld - Friday, February 27, 2026
Home » Topics » Infection, BioWorld Science

Infection, BioWorld Science
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New biphenyl-benzamide derivatives add to potential antibacterial FtsZ inhibitors

Aug. 17, 2022
Researchers from Bioland Laboratory (Guangzhou Regenerative Medicine and Health - Guangdong Laboratory) and the University of Groningen have generated a series of novel biphenyl-benzamides as inhibitors of cell division protein FtsZ with encouraging antibacterial activity.
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New TLR7 agonists disclosed for viral infections

Aug. 16, 2022
Metabrain Research and Shanghai Visonpharma have presented macrocyclic Toll-like receptor 7 (TLR7) agonists reported to be useful for the treatment of hepatitis B virus (HBV), HCV, HIV and influenza virus infections, and cancer.
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Repurposed drug targeting a family of parasitic kinases shows pan-anti-apicomplexan activity

Aug. 16, 2022
Scientists from the University Grenoble Alpes in France and colleagues have recently identified a promising drug candidate with broad-spectrum activity against apicomplexans using a drug repurposing strategy.
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Inhaled AR-701 antibody cocktail shows efficacy in nonhuman primates

Aug. 11, 2022
Aridis Pharmaceuticals announced preclinical data for its inhaled monoclonal antibody (MAb) cocktail, AR-701.
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VIT, BG Negev Technologies and Applications patent NF-kappaB, quorum sensing inhibitors

Aug. 11, 2022
Vellore Institute of Technology University (VIT) and BG Negev Technologies and Applications have described new curcumin or piperine analogues acting as NF-kappaB (NFKB) activation inhibitors and/or quorum sensing signaling inhibitors reported to be useful for treatment of cancer, fungal and bacterial infections and inflammatory disorders.
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Tetra reports ARDS-003 results in live SARS-CoV-2 virus infection studies and septic lung model

Aug. 10, 2022
Tetra Bio-Pharma has announced new promising preclinical results with ARDS-003 (onternabez) from live SARS-CoV-2 virus infection studies, as well as a septic lung model, carried out by independent researchers.
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Shionogi's S-217622 shows in vitro antiviral activity against SARS-CoV-2 Omicron subvariant BA.2.75

Aug. 10, 2022
Shionogi has reported that S-217622 (ensitrelvir fumaric acid), the company's orally administered antiviral drug for COVID-19, shows high in vitro antiviral activity against the SARS-CoV-2 Omicron subvariant BA.2.75.
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NanoViricides to develop NV-387-T for monkeypox virus

Aug. 10, 2022
NanoViricides has outlined plans to develop NV-387-T for monkeypox virus. NV-387-T is made by encapsulating tecovirimat within NV-387 polymeric micelles.
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U.S. Army grant supports HDT Bio's development of HDT-201 as antiviral intranasal spray

Aug. 9, 2022
HDT Bio has been awarded a nearly USD 1.8 million grant from the U.S. Army Medical Research Acquisition Activity to develop HDT-201 into an antiviral intranasal spray that can stimulate the body's innate immune system to treat and prevent a broad spectrum of deadly human viruses.
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SymBio and NINDS collaborate on evaluation of brincidofovir for Epstein Barr virus

Aug. 9, 2022
SymBio Pharmaceuticals has entered into a collaboration agreement with the National Institute of Neurological Disorders and Stroke (NINDS) on the evaluation of brincidofovir's potential antiviral effect on Epstein Barr virus (EBV).
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