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BioWorld - Wednesday, June 10, 2026
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Respiratory

S1P3 receptor at the alveolar-capillary barrier helps drive pulmonary fibrosis

Jan. 15, 2026
No Comments
Pulmonary fibrosis is a chronic, progressive respiratory disease in which the normal barrier between alveoli and capillaries is compromised, leading to persistent injury and inflammation of the lung epithelium.
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Antibody
Immune

Henlius in-licenses anti-IL-1RAP antibody from U-mab Biopharma

Jan. 15, 2026
No Comments
Shanghai Henlius Biotech Inc. has entered into an exclusive global license agreement with U-mab Biopharma (Lianyungang) Co. Ltd., securing rights to a monoclonal antibody (mAb) targeting interleukin-1 receptor accessory protein (IL-1RAP) for inflammatory and autoimmune diseases.
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AI generated illustration of lungs in the human body
Respiratory

Rage Bio enters clinic with inhaled oligonucleotide in COPD

Jan. 14, 2026
By Tamra Sami
No Comments
After raising AU$29 million (US$19.44 million) in a series A round, Rage Biotech Pty Ltd. is beginning phase I trials of its lead candidate, RB-042, an inhaled splice-switching oligonucleotide for treating chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases.
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Inflammatory

Recursion Pharmaceuticals patents PIKfyve inhibitors

Jan. 14, 2026
Recursion Pharmaceuticals Inc. has prepared and tested new 1-phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) inhibitors reported to be useful for the treatment of interstitial lung disease, liver, kidney and myocardial fibrosis.
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And then there was one: Abbvie reaches MFN pricing deal

Jan. 13, 2026
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Abbvie Inc. announced its agreement to focus on improving access and lowering the cost of medicines, becoming the latest pharma to fall in line with the Trump administration’s most-favored nation (MFN) pricing deal. Regeneron Pharmaceuticals Inc. now remains the only firm originally included in President Donald Trump’s July 31 MFN ultimatum that has yet to finalize terms.
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AI generated illustration of lungs in the human body
Newco news

Rage Bio enters clinic with inhaled oligonucleotide in COPD

Jan. 13, 2026
By Tamra Sami
No Comments
After raising AU$29 million (US$19.44 million) in a series A round, Rage Biotech Pty Ltd. is beginning phase I trials of its lead candidate, RB-042, an inhaled splice-switching oligonucleotide for treating chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases.
Read More
AI generated illustration of lungs in the human body
Newco news

Rage Bio enters clinic with inhaled oligonucleotide in COPD

Jan. 12, 2026
By Tamra Sami
No Comments
After raising AU$29 million (US$19.44 million) in a series A round, Rage Biotech Pty Ltd. is beginning phase I trials of its lead candidate, RB-042, an inhaled splice-switching oligonucleotide for treating chronic obstructive pulmonary disease (COPD) and other inflammatory lung diseases.
Read More
Inflammatory

Seed funding at Enodia for targeted protein degradation platform

Jan. 12, 2026
No Comments
Enodia Therapeutics SAS has raised €20.7 million ($25 million) in seed financing to advance its work developing novel small-molecule therapies for targeted protein degradation at the point of synthesis.
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Kazuhide Nakatomi, president and CEO, Hisamitsu

Hisamitsu to go private with $2.5B management buyout

Jan. 9, 2026
By Marian (YoonJee) Chu
No Comments
Hisamitsu Pharmaceutical Co. Inc. President and CEO Kazuhide Nakatomi is leading a management buyout to take the company private, citing mounting drug pricing pressures and tougher listing requirements on the Tokyo Stock Exchange.
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Eli Lilly logo atop Lilly Biotechnology Center campus in San Diego, Calif.

Ventyx’s NLRP3 inhibitors best in class? Lilly offers $1.2B

Jan. 8, 2026
By Karen Carey
No Comments
News of Eli Lilly and Co. purchasing Ventyx Biosciences Inc. for $14 per share arrived after market close Jan. 7, following unconfirmed rumors of the buyout that drove shares up by more than 52% at one point.
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