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BioWorld - Wednesday, December 10, 2025
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 24, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 24, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 22, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
Inflammatory

Beijing Primegene Therapeutics discovers new NEK7 inhibitors

July 22, 2025
Serine/threonine-protein kinase NEK7 inhibitors are described in a recent Beijing Primegene Therapeutics Co. Ltd. patent. They are reported to be useful for the treatment of gout, osteoarthritis, amyotrophic lateral sclerosis, multiple sclerosis, ulcerative colitis, Alzheimer’s, Parkinson’s disease and cancer.
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Inflammatory

DCB-USA, Development Center for Biotechnology report FPR1 antagonists

July 22, 2025
DCB-USA LLC and the Development Center for Biotechnology have patented heterocycle compounds acting as fMet-Leu-Phe receptor (fMLP; FPR1) antagonists reported to be useful for the treatment of cancer, acute respiratory distress syndrome, asthma, arthritis, chronic obstructive pulmonary disease, lung injury, ischemia-reperfusion injury and septicemia.
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Respiratory

MTMR14 downregulation aggravates COPD progression

July 21, 2025
No Comments
Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by chronic inflammation and structural damage to the alveoli, with irreversible declined lung function. M1 pro-inflammatory macrophages mainly participate in airway inflammation and in tissue destruction, and are involved in COPD, but the mechanisms need to be elucidated.
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HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 18, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 17, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
Inflammatory

AC Immune patent discloses new NLRP3 inflammasome inhibitors

July 17, 2025
AC Immune SA has synthesized new heterocyclic modulators acting as NLRP3 inflammasome inhibitors. As such, they are reported to be potentially useful for the treatment of asthma, atherosclerosis, obesity, gout, cryopyrin-associated periodic syndromes, nonalcoholic fatty liver disease (NAFLD), Parkinson’s and Alzheimer’s disease, among others.
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Respiratory

EPAC1 inhibition as an approach for IPF

July 17, 2025
No Comments
Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by lung scarring, fibrosis and finally respiratory failure. Currently, few treatment options are available for IPF and they only slow down disease progression and do not reverse fibrosis. There is a need for new therapeutic targets that aid in the management of the disease.
Read More
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