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BioWorld - Friday, December 19, 2025
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Financial chart, downward arrow

Moonlake shares crash on phase III sonelokimab data for HS

Sep. 29, 2025
By Nuala Moran
No Comments

Bar what it described as a “placebo wobble,” Moonlake Therapeutics AG turned in positive results from the phase III trials of sonelokimab in treating hidradenitis suppurativa (HS), only to see its share price take a complete battering. The stock (Nasdaq:MLTX) fell 90%, or $55.75, to close Sept. 29 at $6.24, after the Zug Switzerland-based company published 16-week data from two identical trials, Vela-1 and Vela-2.


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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Cellular senescence may trigger MS progression

Sep. 29, 2025
By Xavier Bofill Bruna
No Comments
Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 (ECTRIMS 2025) conference, in Barcelona, which ended Sept. 26, addressed this question
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Lab glassware and antibodies art concept
Inflammatory

Tiziana plans to develop IL-6R monoclonal antibody TZLS-501

Sep. 26, 2025
No Comments
Tiziana Life Sciences Ltd. has announced plans to advance its second asset, a fully human anti-IL-6 receptor (IL-6R) monoclonal antibody, TZLS-501.
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Cellular senescence may trigger MS progression

Sep. 26, 2025
By Xavier Bofill Bruna
No Comments
Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 (ECTRIMS 2025) conference, which ends today in Barcelona, addressed this question.
Read More
IPO, coins, financial chart

Genfleet raises $234M with Hong Kong IPO

Sep. 23, 2025
By Marian (YoonJee) Chu
No Comments
Genfleet Therapeutics (Shanghai) Inc. debuted on the Hong Kong Stock Exchange on its second attempt at an IPO, raising HK$1.819 billion (US$234 million). Genfleet’s shares (HKEX:2595) rose to HK$44.00 at the opening bell on Sept. 19 and closed at HK$42.10, about 106% higher than the listing price.
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Syringe in front of Moderna logo

Australia bets on mRNA as Moderna builds regional hub

Sep. 23, 2025
By Tamra Sami
No Comments
While U.S. policymakers are scaling back funding on mRNA vaccine research, Australia is accelerating investment in the technology. At the center of this effort is Moderna Inc., which is establishing an mRNA research and manufacturing footprint in the country and banking on decades of local expertise to bring new therapies to the clinic and serve as a regional hub for Asia Pacific.
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IPO, coins, financial chart

Genfleet raises $234M with Hong Kong IPO

Sep. 19, 2025
By Marian (YoonJee) Chu
No Comments
Genfleet Therapeutics (Shanghai) Inc. debuted on the Hong Kong Stock Exchange on its second attempt at an IPO, raising HK$1.819 billion (US$234 million). Genfleet’s shares (HKEX:2595) rose to HK$44.00 at the opening bell on Sept. 19 and closed at HK$42.10, about 106% higher than the listing price.
Read More
Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immune

Dualitas launches with $65M to advance bispecifics for I&I

Sep. 17, 2025
By Brian Orelli
No Comments
Dualitas Therapeutics Inc. exited stealth mode with a $65 million series A investment that was co-led by Versant Ventures and Qiming Venture Partners USA.
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Kim Kyung-ah, CEO, Samsung Bioepis

South Korea to hike biosimilar approval fees, slash review times

Sep. 16, 2025
By Marian (YoonJee) Chu
No Comments
South Korea’s Ministry of Food and Drug Safety announced Sept. 12 plans to significantly raise drug application fees for biosimilars but slash their review times starting next year.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow

Dualitas launches with $65M to advance bispecifics for I&I

Sep. 16, 2025
By Brian Orelli
No Comments
Dualitas Therapeutics Inc. exited stealth mode with a $65 million series A investment that was co-led by Versant Ventures and Qiming Venture Partners USA.
Read More
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