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BioWorld - Wednesday, May 27, 2026
Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Inflammatory

Forward Therapeutics patents new TNF-α inhibitors

April 8, 2026
No Comments
Forward Therapeutics Inc. has identified new TNF-α inhibitors potentially useful for the treatment of inflammatory disorders and autoimmune diseases.
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Spinal cord
Musculoskeletal

Fortitude unveils lead program for axial spondyloarthritis

April 8, 2026
No Comments
Fortitude Biomedicines Inc. has disclosed that its lead program, FORT-202, is a first-in-class T-cell-targeting bispecific antibody for the potential treatment of axial spondyloarthritis. As a bispecific antibody, FORT-202 is designed to address multiple disease-causing pathways and is expected to significantly improve therapeutic efficacy.
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Cancer and blood cells

Hematopoietic stem cell research points to leukemia’s early roots

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Hematopoietic stem cell research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and inflammation, then, may hold the keys to preventing blood cancers, according to John E. Dick’s plenary session at the 2026 Korean Society of Hematology International Conference, held March 26, 2026.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Cancer and blood cells

Hematopoietic stem cell research points to leukemia’s early roots

April 2, 2026
By Marian (YoonJee) Chu
No Comments
Hematopoietic stem cell research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and inflammation, then, may hold the keys to preventing blood cancers, according to John E. Dick’s plenary session at the 2026 Korean Society of Hematology International Conference, held March 26, 2026.
Read More
PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
Read More
Liver over digital lens background

US FDA warns of liver injuries, 8 deaths associated with Tavneos

April 1, 2026
By Mari Serebrov
No Comments
Once again, Amgen Inc.’s Tavneos (avacopan) is under U.S. FDA scrutiny, as the agency alerted patients and doctors March 31 about 76 cases of drug-induced liver injury, including eight deaths, with “reasonable evidence of a causal association” with the drug.
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Cancer and blood cells
Cancer

Hematopoietic stem cell research points to leukemia’s early roots

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Hematopoietic stem cell (HSC) research over the past century has shown that leukemia may be driven by an invisible hand of inflammation. The bone marrow and inflammation, then, may hold the keys to preventing blood cancers, according to John E. Dick’s plenary session at the 2026 Korean Society of Hematology International Conference (ICKSH 2026), held March 26, 2026. Work in Dick’s lab has found acute myeloid leukemia (AML) HSCs that harbor preleukemic mutations long before any disease diagnosis. These insights have enabled predictive models that could identify individuals at elevated AML risk years before the onset of outright disease, opening the door to new prevention strategies.
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Handshake icon engraved on metal hexagonal background

Galapagos enters new era as Lakefront after reshaping Gilead alliance

March 31, 2026
By Nuala Moran
No Comments
Galapagos NV is about to bury its recent turbulent past and sail off for the future with its $3 billion cash pile and the new name of Lakefront Biotherapeutics NV. The foundation for the transition was laid earlier this month in an arrangement with Gilead Sciences Inc., holder of 25% of Galapagos’ equity, to “co-parent” the assets of Ouro Medicines LLC, which Gilead is acquiring for up to $2.17 billion.
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Inflammatory

Sichuan Kelun-Biotech identifies new glucocorticoid receptor agonists

March 30, 2026
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has discovered new glucocorticoid receptor (GR) agonists potentially useful for the treatment of rheumatoid arthritis, idiopathic arthritis, systemic lupus erythematosus, asthma, ulcerative colitis, neuromyelitis optica and autoimmune liver disease.
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