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BioWorld - Friday, June 2, 2023
Home » Topics » Disease categories and therapies » Obstetrics

Obstetrics
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Pregnant woman
Obstetrics

Comanche’s siRNA therapy CBP-4888 cleared by FDA to enter clinic for pre-eclampsia

March 31, 2023
No Comments
Comanche Biopharma Corp. has received IND clearance from the FDA to conduct a first-in-human study of CBP-4888, its novel, small interfering ribonucleic acid (siRNA) therapy to treat pre-eclampsia.
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A young C. elegans adult
Genetic/Congenital

Proteostasis disruption links menopause to aging in C. elegans

Oct. 25, 2022
By Anette Breindl
No Comments

Disrupted meiosis, the cell division process that leads to the production of reproductive cells in sexually reproducing organisms, led to a decline in overall health by triggering an accelerating aging signature in the roundworm Caenorhabditis elegans.

The work is “the first direct evidence that manipulating the health of reproductive cells leads to premature aging and a decline in healthspan,” senior author Arjumand Ghazi, an associate professor of pediatrics, developmental biology, and cell biology and physiology at the University of Pittsburgh and the University of Pittsburgh Medical Center (UPMC) Children’s Hospital, said in a press release.
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Blood pressure cuff.png
Obstetrics

Vicore selects AT2R agonist C-103 as drug candidate

Oct. 13, 2022
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Vicore Pharma Holding AB has selected C-103 as...
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Technician conducting fetal ultrasound

Sonio raises $5M to develop AI platform for fetal ultrasound diagnostics

July 12, 2022
By Bernard Banga
No Comments
Sonio SAS raised just over $5 million in its seed round to develop artificial intelligence (AI) software allowing health care professionals to determine the most appropriate pregnancy care. Its Sonio Diagnostic software delivers decision support for fetal ultrasound used in antenatal diagnostics.
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Cristina Hickman in embryology lab

A fertile field: Aivf raises $25M as Fairtility receives CE mark

July 5, 2022
By Annette Boyle
No Comments
Two Israeli companies aiming to improve in vitro fertilization (IVF) success rates received good news recently, with Aivf Ltd. hauling in $25 million in a series A round for Ema, its IVF software platform, and Fairtility Ltd. gaining CE mark for its CHLOE EQ embryo quality decision-support tool.
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CHLOE system images showing various blastocyst development

Fairtility’s AI-based system outperforms experts in selection of implantable embryos for IVF

April 8, 2022
By Annette Boyle
No Comments
Fairtility Ltd.’s artificial intelligence (AI)-trained embryo classification system offers patients struggling with infertility and their physicians a better way to maximize the likelihood of implantation following in vitro fertilization (IVF) without the risk of a multiple pregnancy, a study in the Nature portfolio journal Scientific Reports found.
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Female health professional holding Truscreen device

Truscreen’s AI cervical cancer screening tool showing promise for primary screening

April 8, 2022
By Tamra Sami
No Comments
Truscreen Group Ltd. completed its largest clinical trial to date that showed its cervical cancer screening device surpassed liquid-based cytology (LBC) screening in 15,651 women across 64 hospitals in nine provinces in China over three years.
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Endotest kit components

Ziwig develops saliva-based diagnostic test for endometriosis based on microRNAs

March 1, 2022
By Bernard Banga
No Comments
PARIS – Ziwig SAS has developed the Endotest saliva test, for quickly detecting endometriosis. François Golfier, head of the gynecology-obstetrics department at Angers University Hospital and chairman of the endometriosis committee for the National College of French Gynecologists and Obstetricians, claims this new generation of in vitro diagnostic medical devices is going to be a game-changer “as it finally allows this chronic debilitating disease to be detected sooner and within the space of just a few days.”
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Infographic demonstrating products in Cook Medical's Reproductive Health portfolio

Cooper acquires Cook’s reproductive health lines for $875M

Feb. 8, 2022
By Annette Boyle
No Comments
The Cooper Companies Inc. plans to acquire the entirety of Cook Medical Inc.’s reproductive health business in this fiscal quarter for $675 million at closing plus $200 million paid in four $50 million annual installments. The acquisition will expand Cooper’s presence in the Asia-Pacific region. The Cook deal will also accelerate Cooper’s labor and delivery medical device efforts by adding 115 people sales, marketing, education and support staff globally.
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Fetus, RNA concept image

Mirvie touts new data on preterm birth prediction for its personalized pregnancy health test

Feb. 4, 2022
By Catherine Longworth
No Comments
San Francisco-based startup Mirvie Inc. has released data demonstrating how its RNA platform technology can predict preterm birth. The research, presented at the Society for Maternal-Fetal Medicine 42nd Annual Pregnancy Meeting (SMFM 2022), showed the company’s test predicted the condition months before symptoms occurred and identified biological pathways that drive changes in pregnancy.
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