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Home » Topics » Disease categories and therapies » Gynecology/obstetrics

Gynecology/obstetrics
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Figure comparing normal pregnancy to peripartum cardiomyopathy preeclampsia

Mirvie offers preeclampsia risk prediction in US

May 14, 2025
By Annette Boyle
Mirvie Inc. continues the development of precision medicine for pregnancy-related conditions with its Encompass blood test to predict preeclampsia risk and individualized support to head off the life-threatening complication that affects one in 12 pregnancies. The test, which received U.S. FDA breakthrough device designation in 2022, is now available to order online with clinician review via telehealth.
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Illustration of cell dividing
Cancer

Germline variants’ impact on pan-cancer proteome

April 25, 2025
By Mar de Miguel
A large-scale study has revealed the impact of germline variants on proteins in 10 cancer types. Scientists from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) conducted a precision proteogenomic analysis in a pan-cancer study with data from 1,064 patients, identifying tumor heterogeneity and tumorigenesis associated with heritable genetic alterations.
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Illustration of cell dividing
Cancer

Germline variants’ impact on pan-cancer proteome

April 22, 2025
By Mar de Miguel
A large-scale study has revealed the impact of germline variants on proteins in 10 cancer types. Scientists from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC) conducted a precision proteogenomic analysis in a pan-cancer study with data from 1,064 patients, identifying tumor heterogeneity and tumorigenesis associated with heritable genetic alterations. The results provide a broad view of cancer risk that could be useful for patient stratification and the design of prevention strategies.
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Illustration of female reproductive system with polycystic ovary
Women's health

First atlas of the endometrium with polycystic ovary syndrome

April 4, 2025
By Mar de Miguel
Although the causes of polycystic ovary syndrome (PCOS) are unclear, researchers know this condition leads to endometrial dysfunction in women who have hormonal imbalances, and insulin resistance. Now, a study led by scientists at the Karolinska Institutet in Sweden has revealed the cellular and genetic differences that distinguish this disorder in the first atlas of the human endometrium during the proliferative phase of the menstrual cycle.
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Illustration of female reproduction system
Gynecology/obstetrics

Targeting miR-148a-3p identified as a potential therapeutic strategy for uterine fibroids

March 27, 2025
In a recently published study, researchers from the International Centre for Genetic Engineering and Biotechnology in Italy used data from a previous high-throughput screening using human miRNA mimics and selected miR-148a-3p as a therapeutic target.
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Partial view of woman holding paper made intestines over stomach

Uresta raises $3M to stop urinary leaks

March 26, 2025
By Annette Boyle
Resilia Inc., dba Uresta, raised $3 million to launch its device to stop stress urinary incontinence in women. The flexible, insertable device braces the bladder and compresses the urethral passage to reduce or eliminate leakage during exercise, when coughing or laughing or when a woman just doesn’t want to worry about it. BDC Capital led the funding with a $1.5 million investment.
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SonioAI

US FDA clears Sonio Suspect for fetal anomaly detection

Feb. 24, 2025
By Annette Boyle
The U.S. FDA hasn’t taken up criminal justice as a sideline, but it did just clear Sonio Suspect. Far from a social miscreant, Suspect improves detection of fetal anomalies by 22 points by automatically detecting multiple types of abnormal findings and allows for detection as early as 11 weeks of gestation.
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Human sperm image

Posterity looks to future with $13M round for male fertility care

Feb. 19, 2025
By Annette Boyle
Fifty percent of infertility cases arise from issues with the male partner, but standard protocols often delay the first assessment of males for at least two years. Posterity Health Inc. aims to usher in a new generation of fertility care starting with its just-closed $13 million series A financing round.
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Roche building

​US FDA clears Roche’s preeclampsia test

Feb. 14, 2025
By Annette Boyle
With rates of preeclampsia skyrocketing, the U.S. FDA’s510(k) clearance of Roche Holding AG’s Elecsys test for preeclampsia offers some hope of reducing the number of women and infants who die or experience life-long consequences from the development of dangerously high blood pressure during late pregnancy and in the days immediately following delivery.
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Ziwig Endotest

France grants Ziwig Endotest fast-track reimbursement

Feb. 13, 2025
By Annette Boyle
Ziwig SAS, which leads the race for a simple diagnostic for endometriosis, picked up the pace with a fast-track reimbursement decision in France for its Endotest, the first saliva-based diagnostic assay for endometriosis.
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