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Home » Topics » Disease categories and therapies » Gynecology/obstetrics

Gynecology/obstetrics
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Ultrasound photo and pregnancy test on mantle with Christmas garland
Women's health

Scientists deliver the latest advances in pregnancy health

Dec. 31, 2024
By Mar de Miguel
Around the end of every year, the media reports on pregnancy and women who give birth on the last and first days of the new year. They tell their stories, the names of their babies and the cities where they were born. While 2024 was coming to an end, gynecologists and other researchers finalized their publications to improve the health of women and their babies. The formation of the placenta or the study of preeclampsia are some of the first and last stories that greet and say goodbye to 2024. Those of 2025 will be born soon.
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Fallopian tubes, ovaries and uterus
Gynecology/obstetrics

CCNA2 deficiency impairs endometrial responsiveness to steroids

Dec. 20, 2024
Cyclins regulate steroid receptor action in cyclin-dependent kinase (CDK)-dependent and independent manners. In addition to regulating the cell cycle, cyclin A2 (CCNA2) also mediates female sex steroids 17 β-estradiol and progesterone signaling in vitro, which is essential for fertility.
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Illustration of VEGF-A protein molecule
Women's health

Experimental mRNA gene therapy suppresses preeclampsia in mice

Dec. 17, 2024
By Mar de Miguel
A gene therapy based on an enhanced lipid nanoparticle (LNP) loaded with vascular endothelial growth factor (VEGF) mRNA could be developed for the treatment of preeclampsia, according to a study in mice in which it alleviated maternal hypertension until the end of gestation and improved fetal health. Preeclampsia is a disease that affects 3% to 5% of pregnant women, who suffer from hypertension and proteinuria, elevated levels of protein in the urine, during pregnancy.
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Medically accurate illustration of a baby in the womb of a pregnant mother

Nua Surgical raises €6.5M for C-section retractor

Dec. 9, 2024
By Shani Alexander
Nua Surgical Ltd. secured €6.5 million ($6.9 million) in series A financing to support regulatory clearance in the U.S. and early commercialization of its Stericision C-section retractor. The device is a self-retaining surgical retractor designed to improve outcomes for mothers undergoing a caesarean section.
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Illustration of dividing breast cancer cell
Women's health

Estrous cycle alters murine breast cancer response to chemotherapy

Dec. 6, 2024
By Mar de Miguel
In breast cancer, neoadjuvant chemotherapy reduces the tumor before surgery. However, the response to this treatment does not depend solely on the subtype of malignancies. Other factors could play a key role in its effectiveness, as shown in a study that described how the estrous cycle phases contribute to this variation.
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Illustration of dividing breast cancer cell

Estrous cycle alters murine breast cancer response to chemotherapy

Dec. 5, 2024
By Mar de Miguel
In breast cancer, neoadjuvant chemotherapy reduces the tumor before surgery. However, the response to this treatment does not depend solely on the subtype of malignancies. Other factors could play a key role in its effectiveness, as shown in a study that described how the estrous cycle phases contribute to this variation. The researchers propose adjusting the approach to the most suitable moment for patients.
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Illustration of dividing breast cancer cell
Women's health

Estrous cycle alters murine breast cancer response to chemotherapy

Dec. 4, 2024
By Mar de Miguel
In breast cancer, neoadjuvant chemotherapy reduces the tumor before surgery. However, the response to this treatment does not depend solely on the subtype of malignancies. Other factors could play a key role in its effectiveness, as shown in a study that described how the estrous cycle phases contribute to this variation. The researchers propose adjusting the approach to the most suitable moment for patients.
Read More
D-rendered image showing atlas of human embryonic skeletal development
Drug design, drug delivery & technologies

More than 100M cells included in the human cell atlas

Nov. 26, 2024
By Mar de Miguel
An international consortium of thousands of scientists is creating the Human Cell Atlas, a three-dimensional map of all the cells in the body. The goal is to understand all the cells that make up human tissues, organs and systems, which will enable multiple medical applications. This collection of cell maps is openly available for navigation at single-cell resolution, identified through omics analyses that reveal the tridimensional distribution of each cell.
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Gynecology/obstetrics

Shandong Luye Pharmaceutical discovers new GNRHR antagonists

Nov. 26, 2024
Shandong Luye Pharmaceutical Co. Ltd. has described gonadotropin-releasing hormone receptor (GNRHR) antagonists reported to be useful for the treatment of acne, cancer, dysmenorrhea, endometriosis, uterine fibroids (myoma), infertility, precocious puberty and premenstrual syndrome, among others.
Read More
D-rendered image showing atlas of human embryonic skeletal development
Drug design, drug delivery & technologies

More than 100M cells included in the human cell atlas

Nov. 21, 2024
By Mar de Miguel
An international consortium of thousands of scientists is creating the Human Cell Atlas, a three-dimensional map of all the cells in the body. The goal is to understand all the cells that make up human tissues, organs and systems, which will enable multiple medical applications. This collection of cell maps is openly available for navigation at single-cell resolution, identified through omics analyses that reveal the tridimensional distribution of each cell.
Read More
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