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BioWorld - Friday, December 12, 2025
Home » Topics » Disease categories and therapies » Oncology

Oncology
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Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 10, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
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Antibodies

Abbvie gains rights to IGI’s trispecific ISB-2001 in $1.9B+ deal

July 10, 2025
By Karen Carey
No Comments
Nearly six years after Ichnos Sciences Inc. launched operations, a subsidiary of the now-named Ichnos Glenmark Innovation (IGI) Inc. has signed with Abbvie Inc. a global licensing partnership for trispecific antibody ISB-2001 worth $1.925 billion plus royalties. ISB-2001, which targets BCMA, CD38 and CD3, is in a phase I trial for relapsed/refractory multiple myeloma and has orphan drug and fast track status in the U.S
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Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 9, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
Read More
Lunit

Lunit, Microsoft to codevelop cloud-based clinical AI solutions

July 3, 2025
By Marian (YoonJee) Chu
Lunit Inc. reported a new collaboration with Microsoft Corp. July 2 to jointly develop medical AI programs accessible on Microsoft’s Azure cloud platform.
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Woman receiving chemotherapy

Chemotherapy-induced mutations are not universal phenomenon

July 3, 2025
By Nuala Moran
No Comments
The first systematic whole genome sequencing study of how chemotherapy damages healthy tissues has shown that many, but not all, of these agents cause mutations and premature aging of normal blood cells.
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Lei Qian, clinical vice president, Innovent

Innovent raises HKD$4.3B to advance R&D pipeline, global expansion

July 1, 2025
By Tamra Sami
No Comments
Innovent Biologics Inc. announced a HKD$4.3 billion (US$547 million) placement on the Hong Kong Stock Exchange to advance its R&D projects and to fund its global expansion.
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U.S. Supreme Court

Supreme Court upholds ACA’s preventive care coverage

June 27, 2025
By Annette Boyle
The U.S. Supreme Court preserved the U.S. Preventative Services Task Force coverage mandate that requires payers to cover certain preventive services at no cost to patients in a 6-3 ruling. That’s very good news for many diagnostics companies including Exact Sciences Corp. and Guardant Health Inc. as well as companies that manufacture HIV pre-exposure prophylaxis (PReP) medications such as Gilead Sciences Inc.
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Lei Qian, clinical vice president, Innovent

Innovent raises HKD$4.3B to advance R&D pipeline, global expansion

June 26, 2025
By Tamra Sami
No Comments
Innovent Biologics Inc. announced a HKD$4.3 billion (US$547 million) placement on the Hong Kong Stock Exchange to advance its R&D projects and to fund its global expansion.
Read More
Businessman and IPO virtual screen

Caris settles IPO at $21, trading starts at $28

June 20, 2025
By Annette Boyle
Despite raising the price of its IPO twice, Caris Life Sciences Inc. left money on the table with a 33% increase in price as soon as trading commenced on the Nasdaq, though no one is squawking about raising nearly $500 million. The cancer diagnostics company initially priced its IPO at $16 to $18, then raised it to $19 to $20, before closing on a price of $21 per share. As management rang the bell for the start of trade on June 18, shares began trading at $28.
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Enterome raises $19M to advance non-Hodgkin lymphoma therapy

June 13, 2025
By Nuala Moran
No Comments
As it prepares to present the latest data from the phase I/II clinical trial of EO-2463, Enterome SA has secured $19 million to expand and complete the study, and to scope phase III development of the microbiome-derived off-the-shelf immunotherapy in the treatment of non-Hodgkin lymphoma.
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