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BioWorld - Wednesday, December 10, 2025
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Immuno-oncology

Sichuan Kelun-Biotech divulges new HER2-targeting ADCs

Dec. 10, 2024
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has synthesized antibody-drug conjugates.
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Immuno-oncology

DLK1-directed immunotherapy shows activity in neuroblastoma models

Dec. 10, 2024
Researchers from the Children's Hospital of Philadelphia presented data from a study that aimed to identify novel biologically relevant cell surface immunotherapeutic targets for neuroblastoma.
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GSK inks $1B option agreement for Dualitybio preclinical ADC candidate

Dec. 4, 2024
By Tamra Sami
Duality Biologics is out-licensing preclinical antibody-drug conjugate (ADC) candidate DB-1324 under an option agreement with GSK plc potentially worth more than $1 billion.
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Immuno-oncology

Duality Biologics and GSK enter option agreement for ADC DB-1324

Dec. 4, 2024
Duality Biologics (Suzhou) Co. Ltd. has entered into an exclusive option agreement with GSK plc.
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3D illustration demonstrating antibody-drug conjugate.

Tubulis inks $415M ADC collaboration with Gilead

Dec. 3, 2024
By Nuala Moran
Tubulis GmbH has sealed a potential $415 million option and licensing deal under which it will apply proprietary technologies to discover an antibody-drug conjugate (ADC) against a solid tumor target for Gilead Sciences Inc.
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Kelun Biotech rendering of sacituzumab tirumotecan

China approves Kelun-Biotech’s TROP2 ADC for breast cancer

Dec. 3, 2024
By Marian (YoonJee) Chu
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. won local approval of the first China-made trophoblast cell-surface antigen 2 (TROP2)-targeted antibody-drug conjugate (ADC), sacituzumab tirumotecan, as a third-line therapy for advanced breast cancer.
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Kelun Biotech rendering of sacituzumab tirumotecan

China approves Kelun-Biotech’s TROP2 ADC for breast cancer

Dec. 2, 2024
By Marian (YoonJee) Chu
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. won local approval of the first China-made trophoblast cell-surface antigen 2 (TROP2)-targeted antibody-drug conjugate (ADC), sacituzumab tirumotecan, as a third-line therapy for advanced breast cancer.
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Concept art for targeting cancer
Cancer

PYX-201 demonstrates antitumor activity across sarcoma subtypes

Nov. 26, 2024
Researchers from Pyxis Oncology Inc. presented preclinical data for PYX-201, an antibody drug conjugate (ADC) that targets extra domain B of fibronectin (EDB+FN).
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Light micrograph of fibrosarcoma, a type of soft tissue sarcoma
Cancer

Collagen receptor uPARAP-targeted ADCs are active in sarcoma models

Nov. 25, 2024
Researchers from KU Leuven presented novel urokinase plasminogen activator receptor-associated protein (uPARAP)-targeted antibody-drug conjugates (ADC), ADCE-017 and ADCE-202, being developed for the treatment of soft tissue sarcoma.
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3D rendering of drug linked to antibody
Immuno-oncology

Series B financing at Adcendo to fund ADC pipeline

Nov. 25, 2024

Adcendo ApS has closed an oversubscribed $135 million series B financing round to support its development of first-in-class antibody-drug conjugates (ADCs) for the treatment of cancers with a high unmet medical need.


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