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BioWorld - Friday, January 2, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Cstone’s ROR1 ADC chases Merck’s, plus China biotech data: ASH 24

Dec. 10, 2024
By Marian (YoonJee) Chu
Four Chinese biopharmaceuticals unveiled early data on respective cancer therapies at the American Society of Hematology (ASH) 2024 meet in San Diego, including Cstone Pharmaceuticals Co. Ltd.’s receptor tyrosine kinase-like orphan receptor 1 (ROR1)-inhibiting antibody-drug conjugate (ADC) in phase I study for lymphomas.
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Immuno-oncology

Sichuan Kelun-Biotech divulges new HER2-targeting ADCs

Dec. 10, 2024
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has synthesized antibody-drug conjugates.
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Immuno-oncology

DLK1-directed immunotherapy shows activity in neuroblastoma models

Dec. 10, 2024
Researchers from the Children's Hospital of Philadelphia presented data from a study that aimed to identify novel biologically relevant cell surface immunotherapeutic targets for neuroblastoma.
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GSK inks $1B option agreement for Dualitybio preclinical ADC candidate

Dec. 4, 2024
By Tamra Sami
Duality Biologics is out-licensing preclinical antibody-drug conjugate (ADC) candidate DB-1324 under an option agreement with GSK plc potentially worth more than $1 billion.
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Immuno-oncology

Duality Biologics and GSK enter option agreement for ADC DB-1324

Dec. 4, 2024
Duality Biologics (Suzhou) Co. Ltd. has entered into an exclusive option agreement with GSK plc.
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3D illustration demonstrating antibody-drug conjugate.

Tubulis inks $415M ADC collaboration with Gilead

Dec. 3, 2024
By Nuala Moran
Tubulis GmbH has sealed a potential $415 million option and licensing deal under which it will apply proprietary technologies to discover an antibody-drug conjugate (ADC) against a solid tumor target for Gilead Sciences Inc.
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Kelun Biotech rendering of sacituzumab tirumotecan

China approves Kelun-Biotech’s TROP2 ADC for breast cancer

Dec. 3, 2024
By Marian (YoonJee) Chu
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. won local approval of the first China-made trophoblast cell-surface antigen 2 (TROP2)-targeted antibody-drug conjugate (ADC), sacituzumab tirumotecan, as a third-line therapy for advanced breast cancer.
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Kelun Biotech rendering of sacituzumab tirumotecan

China approves Kelun-Biotech’s TROP2 ADC for breast cancer

Dec. 2, 2024
By Marian (YoonJee) Chu
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. won local approval of the first China-made trophoblast cell-surface antigen 2 (TROP2)-targeted antibody-drug conjugate (ADC), sacituzumab tirumotecan, as a third-line therapy for advanced breast cancer.
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Concept art for targeting cancer
Cancer

PYX-201 demonstrates antitumor activity across sarcoma subtypes

Nov. 26, 2024
Researchers from Pyxis Oncology Inc. presented preclinical data for PYX-201, an antibody drug conjugate (ADC) that targets extra domain B of fibronectin (EDB+FN).
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Light micrograph of fibrosarcoma, a type of soft tissue sarcoma
Cancer

Collagen receptor uPARAP-targeted ADCs are active in sarcoma models

Nov. 25, 2024
Researchers from KU Leuven presented novel urokinase plasminogen activator receptor-associated protein (uPARAP)-targeted antibody-drug conjugates (ADC), ADCE-017 and ADCE-202, being developed for the treatment of soft tissue sarcoma.
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