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BioWorld - Sunday, April 19, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Dollar sign in light bulb on yellow background
Cancer

Stipple launches with $100M for novel oncology targets

April 7, 2026
By Brian Orelli
No Comments
Stipple Bio Inc. raised $100 million in a series A financing to support progression of the company’s lead drug, STP-100, an antibody-drug conjugate that binds an undisclosed target, and the company’s Pointillist discovery platform. The round was co-led by RA Capital, a16z Bio+Health and Nextech Invest. Existing investors, including Emerson Collective Investments (managed by Yosemite), GV (Google Ventures), Lola Capital Partners, GordonMD Global Investments and others, also participated in the round.
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Illustration of antibodies targeting cancer cell
Immuno-oncology

Next-generation anti-CD30 ADC outperforms brentuximab vedotin

April 7, 2026
No Comments
Researchers from Mabqi SAS presented the preclinical profile of MQI-181, an antibody-drug conjugate (ADC) composed of a human anti-CD30 antibody (18D03) linked to the cytotoxic payload monomethyl auristatin E (MMAE) via a cleavable MC-VC-PAB linker, with a drug-antibody ratio of 4.
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Illustration of magnifying glass and antibodies
Immuno-oncology

Canwell gains IND clearance for ADC CAN-016

April 7, 2026
No Comments
Canwell Pharma Inc. has obtained IND approval from the FDA for CAN-016, a novel antibody-drug conjugate (ADC). The company will initiate a phase I study in patients with HER2-expressing solid tumors who have experienced disease progression following prior ADC therapies.
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3D rendering of antibody drug conjugated with cytotoxic payload
Immuno-oncology

Akari Therapeutics partners with Wuxi XDC on ADC payload

April 7, 2026
No Comments
Akari Therapeutics plc has established a strategic partnership with Wuxi XDC Cayman Inc. to accelerate the development of Akari’s novel PH1 payload. Akari’s lead program, AKTX-101, is initially targeting metastatic urothelial cancer.
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Dollar sign in light bulb on yellow background

Stipple launches with $100M for novel oncology targets

April 6, 2026
By Brian Orelli
No Comments
Stipple Bio Inc. raised $100 million in a series A financing to support progression of the company’s lead drug, STP-100, an antibody-drug conjugate that binds an undisclosed target, and the company’s Pointillist discovery platform.
Read More
Cancer

New antibody-drug conjugates reported in Biocad patent

April 2, 2026
Biocad Ltd. has disclosed new antibody-drug conjugates consisting of antibodies covalently linked to cytotoxic drugs through linkers reported to be useful for the treatment of cancer.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Cancer cells under magnifying glass

Idel raises $10.4M for intracellular pan-cancer drug delivery tech

March 26, 2026
By Nuala Moran
No Comments
Newco Idel Therapeutics GmbH has closed a €9 million (US$10.4 million) seed round to advance the development of a technology for delivery of cytotoxic drugs directly into the cytosol of tumor cells.
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Immuno-oncology

Glyconex and Nippon Kayaku collaborate on GNX201-ADC

March 24, 2026
No Comments
Glyconex Inc. has entered into a collaboration agreement with Nippon Kayaku Co. Ltd. to advance GNX201-ADC, a next-generation glycan-directed antibody-drug conjugate (ADC) candidate for the treatment of solid tumors.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

Kelun-Biotech’s SKB-103 cleared to enter clinic in China

March 24, 2026
No Comments
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has announced IND approval by China’s National Medical Products Administration (NMPA) for SKB-103 for the treatment of advanced solid tumors.
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