After a shaky start to the year, Autolus Therapeutics plc has revived its fortunes, with Blackstone Life Sciences investing up to $250 million to fund its CAR T-cell technology and lead product targeting acute lymphoblastic leukemia.
Marengo Therapeutics Inc. is opening up a new front in the war on cancer by selectively deploying a tumor-infiltrating subpopulation of T cells, which can be activated by a newly identified, antibody-based mechanism. The Cambridge, Mass.-based company is taking forward a scientific concept that has been germinating for several years at founding investor and company creator ATP, which has now launched the firm with an $80 million series A round. Marengo is gearing up for a first clinical trial in 2022. “It’s a new chapter in T-cell biology,” CEO Zhen Su told BioWorld.
DUBLIN – As its name suggests, Glycoera AG aims to kickstart a new era in protein glycoengineering, and it has closed a CHF45 million (US$49 million) series A round to further its ambition of developing biologic drugs with defined glycosylation profiles that are an intrinsic aspect of their mechanisms.
Sichuan Clover Biopharmaceuticals Inc. raised HK$2.03 billion (US$260.17 million) in its Hong Kong Stock Exchange debut. Shares closed at HK$12.98 (US$1.67) on Nov. 5 after trading as high as HK$13.56 earlier.
Biopharmas raising money in public or private financings, including: Blue Water Vaccines, Cardiol, Evaxion, Intelligent Medicine Acquisition, IO Biotech, Mainz Biomed, Nervgen, Tetra. Vaxxinity, Viracta.
Biopharmas raising money in public or private financings, including: Ani, Cellenkos, Concert, Evotec, Mission, Oramed, Orphazyme, Parthenon, Plateletbio.
Antios Therapeutics Inc. followed up its $96 million series B financing in April with another $75 million series B-1 round that reflects faith in the potential of lead candidate ATI-2173, bound for phase IIb investigation as the backbone of a once-daily, curative regimen in chronic hepatitis B virus (HBV) infection.