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BioWorld - Tuesday, April 7, 2026
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Medically accurate illustration of a baby in the womb of a pregnant mother

AI used to ID abnormalities in unborn babies

March 31, 2025
By Shani Alexander
The use of an AI tool could speed up the time it takes to do pregnancy scans by almost half and it is still able to identify any abnormalities in the fetus, researchers found. Results from a study showed the AI tool used to assist with 20-week pregnancy scans reduced the scan length by more than 40% and still maintained the same accuracy and reliability of diagnoses.
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Pep-Therapy advancing orphan drug PEP-010 in pancreatic cancer

March 31, 2025
By Nuala Moran
French biotech Pep-Therapy SAS is in the midst of raising a €20 million (US$21.62 million) round and, at the same time, prospecting for potential partners after winning FDA orphan drug designation for its bifunctional peptide Pep-010 in the treatment of pancreatic cancer. Pep-010 currently is moving to the conclusion of a phase Ib trial and the new money will fund phase II development.
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Doctor measuring patient's waist
Endocrine/metabolic

Novo Nordisk licenses Lexicon’s preclinical obesity drug in $1B deal

March 31, 2025
By Karen Carey
As companies continually search for next-generation obesity prospects, one of the leaders in the disease space, Novo Nordisk A/S, has obtained an exclusive license to a preclinical-stage, first-in-class, small-molecule inhibitor of Acyl-CoA synthetase 5 (ACSL5) developed by Lexicon Pharmaceuticals Inc.
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Daewoong researchers in the lab

Daewoong sees end of CS Pharma deal; new starts in cancer, DTx

March 28, 2025
By Marian (YoonJee) Chu
It was a mixed day for Daewoong Pharmaceutical Co. Ltd., which disclosed separately on March 28 both the termination of a $336 million licensing deal with CS Pharmaceuticals Ltd. and upbeat plans to unveil three new oncology assets at the upcoming American Association for Cancer Research in April.
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Doctor measuring patient's waist

Novo Nordisk licenses Lexicon’s preclinical obesity drug in $1B deal

March 28, 2025
By Karen Carey
As companies continually search for next-generation obesity prospects, one of the leaders in the disease space, Novo Nordisk A/S, has obtained an exclusive license to a preclinical-stage, first-in-class, small-molecule inhibitor of Acyl-CoA synthetase 5 (ACSL5) developed by Lexicon Pharmaceuticals Inc.
Read More

Alzheimer’s drug Kisunla rejected by European regulators

March 28, 2025
By Nuala Moran
The EMA has rejected the Alzheimer’s disease therapy Kisunla (donanemab) from Eli Lilly and Co., saying the benefits of the anti-amyloid antibody do not outweigh the risks of edema and hemorrhage in the brain, known as amyloid-related imaging abnormalities (ARIA).
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Brain illustrated with pills
Neurology/psychiatric

Disease-modifying Alzheimer’s drugs are ‘drivers of change’

March 28, 2025
By Nuala Moran
The first disease modifying therapies for Alzheimer’s may have limited utility in some senses, but they will be a force for change, providing momentum and altering the way governments as payers, and health systems as carers, think about the disease.
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Abbott Labs Volt

Abbott’s Volt enters the PFA fray with CE mark

March 27, 2025
By Annette Boyle
Abbott Laboratories snagged a CE mark for its Volt pulsed field ablation catheter for atrial fibrillation several months earlier than the mid-year approval expected. The Abbott Park, Ill.-based company has begun Volt’s commercial launch with the physicians who participated in its European clinical trials and plans to expand to other users on the continent in the second half of 2025.
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Bionicm powered prosthetic leg products

Scientists develop material to improve the fitting of prosthetic limbs

March 27, 2025
By Shani Alexander
Scientists in the U.K. have developed a new meta-material, dubbed Roliner, to improve the fitting of wearable devices made from hard materials, such as prosthetic limbs.
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Brain illustrated with pills
Neurology/psychiatric

Disease-modifying Alzheimer’s drugs are ‘drivers of change’

March 27, 2025
By Nuala Moran
The first disease modifying therapies for Alzheimer’s may have limited utility in some senses, but they will be a force for change, providing momentum and altering the way governments as payers, and health systems as carers, think about the disease.
Read More
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