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BioWorld - Saturday, December 20, 2025
Home » Topics » Patents, BioWorld Science

Patents, BioWorld Science
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Cancer

Shenzhen Zhongge Biotechnology discovers new KIF18A inhibitors

Oct. 17, 2025
Shenzhen Zhongge Biotechnology Co. Ltd. has described kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Cancer

New TEAD inhibitors disclosed in Insilico Medicine patent

Oct. 17, 2025
Insilico Medicine Ltd. has divulged transcriptional enhancer factor (TEAD) inhibitors reported to be useful for the treatment of cancer and fibrosis.
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Endocrine/metabolic

Genescience Pharmaceuticals describes new PAH stabilizers for PKU

Oct. 17, 2025
Genescience Pharmaceuticals Co. Ltd. has identified phenylalanine hydroxylase (PAH) (R408W mutant) stabilizers reported to be useful for the treatment of phenylketonuria (PKU).
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Gastrointestinal

Salubris Pharmaceuticals divulges new MIR124 activators

Oct. 17, 2025
Shenzhen Salubris Pharmaceuticals Co. Ltd. has synthesized compounds acting as MIR124 activators reported to be useful for the treatment of inflammatory bowel disease and inflammatory disorders.
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Inflammatory

Bioage Labs patents new NLRP3 inflammasome inhibitors

Oct. 17, 2025
Bioage Labs Inc. has disclosed NLRP3 inflammasome inhibitors reported to be useful for the treatment of inflammatory disorders.
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Cancer

Korean scientists discover new MDH1 and MDH2 inhibitors

Oct. 16, 2025
Researchers at Dongguk University and Korean Research Institute of Bioscience and Biotechnology have described oxazole derivatives acting as malate dehydrogenase, cytoplasmic (MDH1) and/or malate dehydrogenase, mitochondrial (MDH2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New MYST-3 and -4 inhibitors disclosed in Beone patent

Oct. 16, 2025
Scientists at Beone Medicines I GmbH and Beone Pharmaceutical (Suzhou) Co. Ltd. have divulged histone acetyltransferase KAT6A (MOZ; MYST-3) and histone acetyltransferase KAT6B (MOZ2; MYST-4) inhibitors reported to be useful for the treatment of breast cancer.
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Ocular

Pyrotech Biotechnology describes new GSDME inhibitors

Oct. 16, 2025
Pyrotech (Beijing) Biotechnology Co. Ltd. has identified gasdermin-E (GSDME) inhibitors reported to be useful for the treatment of genetic diseases, cancer, viral infection, age-related macular degeneration, autoimmune diseases, neurological disorders, renal disorders and cancer therapy-associated disorders.
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Cancer

Suzhou Puhe Biopharma divulges new GTPase KRAS mutant inhibitors

Oct. 16, 2025
Suzhou Puhe Biopharma Co. Ltd. has synthesized GTPase KRAS (mutant) inhibitors reported to be useful for the treatment of cancer.
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Inflammatory

Nuphase Therapeutics patents new IL-17A/A homodimer and IL-17A/F heterodimer inhibitors

Oct. 16, 2025
Nuphase Therapeutics (Shanghai) Co. Ltd. has disclosed compounds acting as interleukin-17A/A homodimer and IL-17A/F heterodimer inhibitors reported to be useful for the treatment of cancer, autoimmune and inflammatory diseases.
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