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BioWorld - Thursday, June 12, 2025
Home » Topics » Infection » Coronavirus

Coronavirus
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In the clinic for May 20, 2024

May 20, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Achieve, Astrazeneca, Bayer, BMS, Hutchmed, Inventiva, Marinus, Recce.
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Report leads to suspension of Ecohealth, NIH rebuke

May 16, 2024
By Mari Serebrov
Citing the need to protect the public interest, the U.S. Department of Health and Human Services ordered an immediate government-wide funding suspension May 15 of Ecohealth Alliance Inc. while formal debarment proceedings are pending against the New York-based nongovernmental organization.
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Oral medication

Shionogi’s COVID-19 drug misses endpoint in global phase III

May 14, 2024
By Marian (YoonJee) Chu
Osaka, Japan-based Shionogi & Co. Ltd. said May 13 that ensitrelvir fumaric acid (Xocova), its oral antiviral for COVID-19, showed no statistical difference against placebo in completely resolving 15 common COVID-19-related symptoms in a global phase III Scorpio-HR trial.
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In the clinic for May 14, 2024

May 14, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Ascendis, BMS, Bridgebio, Cardurion, Cytokinetics, Delix, Excision, Imunon, Inventiva, Jasper, Merck & Co., Newron, Senti, Valneva.
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Nuvaxovid

Novavax storms back with $1.2B Sanofi deal

May 10, 2024
By Lee Landenberger
A licensing deal worth potentially up to $1.2 billion with Sanofi SA has breathed new life into Novavax Inc., which has struggled to compete in the COVID-19 space with powerhouses Pfizer Inc. and Moderna Inc.
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Infection

Roche divulges new 3CLpro inhibitors

May 9, 2024
Researchers at F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have synthesized 3C-like proteinase (3CLpro, Mpro) (coronavirus) inhibitors reported to be useful for the treatment of coronavirus acute respiratory syndrome infections.
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In the clinic for May 8, 2024

May 8, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Achieve, Calliditas, Eledon, Eyedna, Inmagene, Mirum, Moleculin, Neurogene, Neurosense, Rion, Traws, Verve.
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Coronavirus, mRNA and syringe
Infection

Astrazeneca presents data on mRNA VLP SARS-CoV-2 vaccine in animal models

May 3, 2024
There is still a need for developing more potent and broadly neutralizing vaccines against SARS-CoV-2 with improved durability. At the recent ESCMID meeting, Astrazeneca plc presented a new mRNA vaccine against the SARS-CoV-2 virus that encodes for self-assembling virus-like particle (VLP) antigens.
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Infection

European researchers patent PROTACs for SARS-CoV-2

May 2, 2024
Tocris Cookson Ltd., Helmholtz Zentrum fur Infektionsforschung GmbH and University of Lübeck have described proteolysis targeting chimeras (PROTACs) comprising cereblon (CRBN) ligands covalently bonded to non-structural protein 3 (nsp3; PL-PRO) (SARS-CoV-2; COVID-19 virus) targeting moiety through linker reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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WHO pandemic deal doesn’t protect developing countries, groups say

April 30, 2024
By Tamra Sami
The latest World Health Organization’s (WHO) Pandemic Agreement falls short of protecting all countries in future pandemics, said international patient groups and public health organizations.
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