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BioWorld - Wednesday, January 7, 2026
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Home » Topics » BioWorld Science, Patents

BioWorld Science, Patents
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Infection

Zhuhai United Laboratories discovers new β-lactamase inhibitors

Nov. 19, 2025
Zhuhai United Laboratories Co. Ltd. has described β-lactamase (bacterial) inhibitors reported to be useful for the treatment of bacterial infections.
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Cancer

New GSPT1/CSNK1A1 degradation inducers disclosed in Mindrank patent

Nov. 19, 2025
Mindrank Therapeutics (Suzhou) New Drug Research & Development Co. Ltd. has divulged molecular glue degraders comprising cereblon (CRBN) ligands acting as dual eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) and casein kinase 1 isoform α (CSNK1A1) degradation inducers. They are reported to be potentially useful for the treatment of cancer, Alzheimer’s disease, inflammatory disorders, autoimmune diseases and metabolic diseases.
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Immuno-oncology

Hutchmed describes new antibody-drug conjugates

Nov. 19, 2025
Hutchmed Ltd. has identified antibody-drug conjugates comprising an antibody or antigen binding fragment covalently linked to a GTPase RAS or KRAS inhibitor through a linker reported to be useful for the treatment of cancer.
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Cancer

Hangzhou Zhongmei Huadong Pharmaceutical divulges new GTPase KRAS inhibitors

Nov. 19, 2025
Hangzhou Zhongmei Huadong Pharmaceutical Co. Ltd. has synthesized GTPase KRAS wild-type and/or its mutant inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Yichang Humanwell Pharmaceutical patents new κ-opioid receptor agonists

Nov. 19, 2025
Yichang Humanwell Pharmaceutical Co. Ltd. has disclosed morphinan derivatives acting as κ-opioid receptor agonists reported to be useful for the treatment of pain and pruritus.
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Immuno-oncology

Shanghai Phrontline Biopharma discovers new antibody-drug conjugates

Nov. 18, 2025
Shanghai Phrontline Biopharma Co. Ltd. has described antibody-drug conjugates comprising an antibody or antigen-binding fragment targeting HER2 (erbB2) covalently linked to a cytotoxic drug through a linker reported to be useful for the treatment of cancer.
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Cancer

New GTPase KRAS mutant inhibitors disclosed in Adlai Nortye patent

Nov. 18, 2025
Adlai Nortye Biopharma Co. Ltd. and Adlai Nortye Pte Ltd. have divulged GTPase KRAS (mutant) inhibitors reported to be useful for the treatment of cancer, inflammatory diseases and immunological disorders.
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Neurology/psychiatric

Idorsia Pharmaceuticals describes new OX2 receptor agonists

Nov. 18, 2025
Idorsia Pharmaceuticals Ltd. has identified aryl sulfone and sulfanone derivatives acting as orexin OX2 receptor (HCRTR2) agonists reported to be useful for the treatment of eating disorders, fatigue, Kleine-Levin syndrome, narcolepsy, obesity, pain, and psychiatric and inflammatory disorders, among others.
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Cancer

Inventisbio divulges new WRN inhibitors

Nov. 18, 2025
Inventisbio Co. Ltd. and Inventisbio LLC have synthesized Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Gastrointestinal

Samjin Pharmaceutical patents new compounds for MASH

Nov. 18, 2025
Samjin Pharmaceutical Co. Ltd. has disclosed inhibitors of 17-β-hydroxysteroid dehydrogenase 13 (HSD17B13; 17-β-HSD 13) and/or estradiol 17-β-dehydrogenase 1 (HSD17B1; 17β-HSD1) and/or HSD17B2 (17β-HSD2). As such, they are believed to be potentially useful for the treatment of nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH).
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