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BioWorld - Wednesday, January 7, 2026
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BioWorld Science, Patents
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Cancer

Novartis discovers new HER2-targeting peptide-drug conjugates

Nov. 14, 2025
Novartis AG has described peptide-drug conjugates comprising cyclic peptides targeting HER2 (erbB2) covalently linked to a radiolabeled metal chelator through a linker reported to be useful for diagnosis and treatment of cancer.
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Endocrine/metabolic

New GIPR antagonists disclosed in Pfizer patent

Nov. 14, 2025
Pfizer Inc. has divulged gastric inhibitory polypeptide receptor (GIPR) antagonists reported to be useful for the treatment of type 2 diabetes and obesity.
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Inflammatory

Abbvie describes new LPAR1 antagonists

Nov. 14, 2025
Abbvie Inc. has identified lysophosphatidic acid receptor 1 (LPAR1; EDG2) antagonists reported to be useful for the treatment of fibrosis and inflammatory disorders.
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Cancer

Nanjing Zaiming Pharmaceutical divulges new WRN inhibitors

Nov. 14, 2025
Nanjing Zaiming Pharmaceutical Co. Ltd. has synthesized Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shouyao patents new MALT1 inhibitors

Nov. 14, 2025
Shouyao Holdings (Beijing) Co. Ltd. has disclosed mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitors reported to be useful for the treatment of cancer, rheumatoid arthritis, multiple sclerosis, psoriasis, Sjögren’s syndrome, systemic lupus erythematosus, erythema and vasculitis.
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Respiratory

Suzhou Junjian Yifang Biopharmaceutical discovers new PDE3/PDE4 inhibitors

Nov. 13, 2025
Suzhou Junjian Yifang Biopharmaceutical Co. Ltd. has described pyrimido[6,1-a]isoquinolin-4-one derivatives acting as dual phosphodiesterase PDE3 and PDE4 inhibitors reported to be useful for the treatment of asthma and chronic obstructive pulmonary disease.
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Cancer

New crystalline salts of POLθ inhibitors disclosed in Synrx patent

Nov. 13, 2025
Hangzhou Synrx Therapeutics Technology Co. Ltd. has divulged crystalline salts of DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Chia Tai Tianqing Pharmaceutical describes new fused bicyclic compounds

Nov. 13, 2025
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has identified fused bicyclic compounds reported to be useful for the treatment of cancer.
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Cancer

3H Pharmaceuticals divulges new WRN inhibitors

Nov. 13, 2025
3H Pharmaceuticals Co. Ltd. has synthesized Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
Read More
Ocular

Innovstone patents new LFA-1/ICAM-1 interaction inhibitors

Nov. 13, 2025
Innovstone Therapeutics Ltd. has disclosed integrin αLβ2 (LFA-1)/ICAM-1 interaction inhibitors and/or RASP-trapping agents reported to be useful for the treatment of dry eye syndrome.
Read More
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