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BioWorld - Tuesday, February 24, 2026
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Cancer

Bionova Pharmaceuticals describes new PRMT5 inhibitors

Sep. 19, 2025
Bionova Pharmaceuticals Ltd. has identified methylthioadenosine (MTA) synergistic protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Shanghai Huilun Pharmaceutical divulges new AT2 antagonists

Sep. 19, 2025
Shanghai Huilun Pharmaceutical Co. Ltd. has synthesized type 2 angiotensin II receptor (AGTR2; AT2) antagonists reported to be useful for the treatment of pain, particularly neuropathic pain.
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Cancer

Bugworks Research India patents new CDK7 inhibitors

Sep. 19, 2025
Bugworks Research India Pvt Ltd. has disclosed cyclin-dependent kinase 7 (CDK7) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Chinese scientists discover new IDH1 inhibitors

Sep. 18, 2025
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences has described isocitrate dehydrogenase (NADP) cytoplasmic (IDH1; PICD; IDP) (mutant) inhibitors reported to be useful for the treatment of glioma.
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Cancer

Chengdu Kanghong Pharmaceutical describes new POLθ inhibitors

Sep. 18, 2025
Chengdu Kanghong Pharmaceutical Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

New PI3Kα mutant inhibitors disclosed in Shanghai Yingli Pharmaceutical patent

Sep. 18, 2025
Shanghai Yingli Pharmaceutical Co. Ltd. has divulged phosphatidylinositol 3-kinase α (PI3Kα) (H1047R mutant) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Nanjing Zaiming Pharmaceutical divulges new WRN inhibitors

Sep. 18, 2025
Nanjing Zaiming Pharmaceutical Co. Ltd. has synthesized Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Dermatologic

Almirall patents new EMT inhibitors

Sep. 18, 2025
Almirall SA has disclosed tyrosine-protein kinase ITK/TSK (EMT) inhibitors reported to be useful for the treatment of atopic dermatitis, psoriasis, alopecia areata, vitiligo, T-cell lymphoma, asthma, inflammatory bowel disease and multiple sclerosis, among others.
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Cancer

MSD and Peloton Therapeutics discover new YAP1/TEAD interaction inhibitors

Sep. 17, 2025
Merck Sharp & Dohme LLC and Peloton Therapeutics Inc. have described transcriptional coactivator YAP1/transcriptional enhancer factor (TEAD) interaction inhibitors reported to be useful for the treatment of cancer.
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Cancer

New HDAC1 inhibitors disclosed in Betta Pharmaceuticals patent

Sep. 17, 2025
Betta Pharmaceuticals Co. Ltd. has divulged histone deacetylase 1 (HDAC1) inhibitors reported to be useful for the treatment of cancer.
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