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BioWorld - Sunday, June 21, 2026
Home » Authors » Brian Orelli

Brian Orelli

Articles

ARTICLES

Hand holding money plant
Newco news

Abvance Therapeutics secures seed funding to limit glucose lows

June 26, 2025
By Brian Orelli
No Comments
Abvance Therapeutics Inc. secured an undisclosed amount of capital in a seed round led by Zubi Capital to support development of an insulin and glucagon combination product that the company has been in the process of developing for approximately 18 months.
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Close-up of nasal drug spraying
Newco news

Mosanna launches with $80M to develop its sleep apnea drug

June 11, 2025
By Brian Orelli
No Comments
Mosanna Therapeutics secured $80 million in a series A round to develop MOS-118 as a treatment for the nearly 1 billion people globally with obstructive sleep apnea (OSA). The company has completed the formulation work to make the drug into a nasal spray and the initial proof-of-concept animal studies and is now ready to enter clinical trials in patients with OSA.
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ASCO 2025: Pancreatic cancer treatment progressing beyond chemotherapy

June 2, 2025
By Brian Orelli
No Comments
At the 61st American Society of Clinical Oncology (ASCO) Annual Meeting, multiple companies presented clinical trial data showing their drugs and devices helped patients with pancreatic cancer live longer or improve their ability to respond to treatment.
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Green and red bispecific antibodies

Biontech trades half of bispecific BNT-327 to BMS for potential $11B+

June 2, 2025
By Brian Orelli
No Comments
Biontech SE and Bristol Myers Squibb Co. are teaming up to develop Biontech’s BNT-327 in a deal possibly worth over $11 billion. BNT-327 is in the hot new class of bispecific antibodies targeting programmed death-1 (PD-1) or its ligand (PD-L1) and vascular endothelial growth factor (VEGF). The bispecifics take advantage of two well established mechanisms of action that help tumors grow; PD-1/PD-L1, which tells immunogenic T cells not to attack the tumor, and VEGF, which tumors excrete to produce new blood vessels to supply oxygen and other nutrients to the tumor.
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23andme saliva collection kit

Regeneron plans to buy 23andme from bankruptcy for $256M

May 19, 2025
By Brian Orelli
No Comments
Regeneron Pharmaceuticals Inc. was the successful bidder for 23andme Holding Co.’s personal genome service, total health and research services business lines, including its biobank and associated assets, in the bankruptcy auction to sell 23andme's assets.
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Therini Bio locks in another $39M for its fibrin-targeting immunotherapies

May 16, 2025
By Brian Orelli
No Comments
Therini Bio raised an additional $39 million in its series A financing round, bringing the total for the round to $75 million. The capital will be used to advance its fibrin-targeting immunotherapies for neurodegenerative diseases.
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Glycomine snags $115M to advance its PMM2-CDG treatment

April 17, 2025
By Brian Orelli
Glycomine Inc. secured $115 million in a series C financing round to support the advancement of GLM-101 into a phase IIb study in patients with phosphomannomutase-2 congenital disorder of glycosylation (PMM2-CDG).
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Newco news

Hillstar launches with $67M series A to target TRBV9+ T cells

March 25, 2025
By Brian Orelli
Hillstar Bio came out of stealth mode, announcing a $67 million series A financing round with investors including Droia Ventures, Frazier Life Sciences, Novo Holdings A/S and Lifearc Ventures.
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Biocom AI panel

Biocom 2025: The quickly evolving AI landscape

Feb. 26, 2025
By Brian Orelli
A panel at Biocom California’s 15th Annual Global Life Science Partnering & Investor Conference covered the emerging use of artificial intelligence (AI) to discover and develop drugs. “We’re in a very different place than we were five years ago, or even three years ago, even two years ago, from our ability to harness AI to make advances,” Marc Tessier-Lavigne, CEO of South San Francisco-based Xaira Therapeutics Inc., told the audience, adding that the development is actually accelerating.
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Windward Bio launches with an in-licensed asset for asthma and COPD

Jan. 10, 2025
By Brian Orelli
Windward Bio AG was established with plans to both license a drug and establish wet labs to create an internal pipeline of drug candidates. SR One, Omega Funds, RTW Investments, Qiming Venture Partners, Quan Capital and Pivotal Bioventure Partners funded the Basel, Switzerland-based company’s $200 million series A financing round.
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