If early human trial results from Inflammagen Therapeutics Inc. are borne out in its new Phase II pilot study, disclosed Monday, the company could have a major blockbuster on its hands, according to CEO John Rodenrys. Read More
WASHINGTON – Stop searching for the perfect way and just do it, a coalition of drugmaker, distributor and pharmacy groups told a House subcommittee last week as it pushed for a uniform, nationwide track-and-trace system for prescription drugs that's practical and feasible. Read More
By combining kidney transplants with a transplant of bone marrow stem cells and so-called facilitating cells, researchers have enabled patients to ditch their immunosuppressive drugs after receiving an HLA-mismatched transplant in a Phase II trial. Read More
Martin Shkreli has never been one to go with the flow. The hedge fund manager at MSMB Capital Management is known for activism: He helped derail the proposed merger between AMAG Pharmaceuticals Inc. and Allos Therapeutics Inc., fought Pfizer Inc.'s decision to replace CEO Jeff Kindler with an insider and has pushed out several health care CEOs he felt weren't doing their jobs. Read More
Earlier this month, Aastrom Biosciences Inc.'s president and CEO, Tim Mayleben, told BioWorld Today that his firm likely would complete a financing this quarter to help support the recently launched Phase III critical limb ischemia (CLI) trial. (See BioWorld Today, March 2, 2012.) Read More
• OPKO Health Inc., of Miami, said it licensed rights to SR 3306, a compound discovered by scientists at the Florida campus of the Scripps Research Institute, which is designed to block the destruction of brain cells in animal models of Parkinson's disease. Read More
• Moberg Derma AB, of Stockholm, Sweden, said the German-Federal Institute for Drugs and Medical Devices granted approval for a Phase I trial of Limtop, a product in development for actinic keratosis, genital warts and basal cell carcinoma. The drug is a new formulation of an immunomodulatory compound that has shown improved delivery to skin tissue in preclinical studies. Read More
Scientists from the Swedish Karolinska Institutet have shown that exercise rapidly altered the methylation patterns of several genes, including those for PPAR-gamma and its coactivator, PGC-1, which regulate fat storage and glucose metabolism. Read More
