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Home » Newsletters » BioWorld

BioWorld

Aug. 1, 2019

View Archived Issues

Janssen quits $730M partnership with Alligator in portfolio shuffle

Sweden's Alligator Bioscience AB said Janssen Biotech Inc. has terminated its 2015 licensure of the Swedish company's CD40-directed antibody, ADC-1013, following a strategic portfolio decision to prioritize other assets.  Read More

Wellington Partners impresses with close of €210M life science fund

LONDON – Wellington Partners has reported the final close of its fifth fund at €210 million (US$234 million), well above the initial target range of €120 million to €150 million. Read More

Third time's a charm: Alizé Pharma 3 closes $75M series A round

DUBLIN – Alizé Pharma 3 SAS closed a €67 million (US$75.7 million) series A round to progress a pair of preclinical assets in development for rare endocrine and metabolic disorders.  Read More

Aclaris' phase II ATI-501 results for alopecia areata fail to convince investors

Achieving statistically significant improvement over placebo with JAK inhibitor ATI-501 didn't satisfy Aclaris Therapeutics Inc.'s shareholders as the stock (NASDAQ:ACRS) dramatically dropped 26.4% on Wednesday.  Read More

HHS, FDA ready to open U.S. door to Rx importation

U.S. Health and Human Services (HHS) Secretary Alex Azar announced Wednesday that HHS and the FDA are finally opening a door Congress provided decades ago to allow prescription drugs to be imported from Canada. Read More

Sichuan's Hinova raises $40M in series B to advance prostate cancer drug to phase III testing

HONG KONG – Chengdu-based Hinova Pharmaceuticals Inc., of China's Sichuan province, closed a series B financing that added $40 million to the company's pocket.  Read More

Clinical AI firm Sensyne partnering with Bayer to improve cardiovascular trials

LONDON – Clinical artificial intelligence (AI) specialist Sensyne Health plc agreed to a two-year collaboration with Bayer AG, in which it will apply its algorithms to analyze 3 million medical records, with the aim of identifying disease subtypes that support patient stratification in phase III trials in cardiovascular disease. Read More

Other news to note

Medicenna Therapeutics Corp., of Toronto, selected long-acting IL-2 MDNA-19 (formerly, MDNA-109-LA1) as its second immuno-oncology clinical candidate.  Read More

Earnings

Ironwood Pharmaceuticals Inc., of Cambridge, Mass., reported Linzess (linaclotide) U.S. net sales, as provided by its U.S. collaboration partner, Allergan plc, of Dublin, were $196 million in the second quarter.  Read More

Regulatory front

The FDA issued a draft guidance Wednesday on general clinical pharmacology considerations for neonatal drug studies as an adjunct to a 2014 draft guidance on pediatric studies.  Read More

Financings

Vaccinex Inc., of Rochester, N.Y., said it entered a stock purchase agreement with a syndicate of new and existing investors for a private placement of 3.38 million shares at $4.08 each for aggregate gross proceeds of approximately $13.8 million.  Read More

Appointments and advancements

Arvinas Inc., of New Haven, Conn., appointed Ronald Peck chief medical officer and Leslie Norwalk to its board. Read More

Clinical data for July 31, 2019

Read More

Regulatory actions for July 31, 2019

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