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Home » Newsletters » BioWorld

BioWorld

Oct. 14, 2024

View Archived Issues
Digital brain and silhouette

Lundbeck gains bexicaserin with $2.6B Longboard buyout

H. Lundbeck A/S is to acquire Longboard Pharmaceuticals Inc. in an all-cash deal valuing the epilepsy specialist at $2.6 billion. The agreed price of $60 per share is a 54% premium to the closing price of Longboard stock (NASDAQ:LBPH) on Oct. 11 and represents the biggest deal in Lundbeck’s 110-year history. The acquisition will give the Copenhagen, Denmark-based pharma company ownership of bexicaserin, which in September entered phase III development in Dravet syndrome. The 5-HT2C agonist has the potential to treat this and other rare developmental and epileptic encephalopathies, for most of which there are no approved therapies. Read More

Pfizer notches another hemophilia approval

The U.S. FDA has approved the second hemophilia drug in nearly six months from Pfizer Inc. This one, Hympavzi (marstacimab), is for preventing or reducing bleeding in those age 12 and older with hemophilia A and B. Hympavzi heralds a couple of market boundary breakers: it’s the first and only anti-tissue factor pathway inhibitor approved in the U.S. for hemophilia A or B and the first hemophilia medicine approved in the U.S. to be administered using a pre-filled, auto-injector pen. Read More
Wooden stamp with China flag

China’s NMPA approves Junshi’s PCSK9 ongericimab

China’s National Medical Products Administration has given the thumbs up to Junshi Biosciences Co. Ltd.’s NDA for ongericimab, a recombinant humanized anti-PCSK9 monoclonal antibody, marking the third PCSK9 inhibitor to be cleared in China. Read More

Jasper rises on promising early briquilimab data in urticaria

Continuing its streak of promising early clinical data, Jasper Therapeutics Inc.’s briquilimab impressed in a preliminary readout from a phase Ib/IIa study in chronic inducible urticaria (CIndU), showing a clinical response of 93%. CIndU, an inflammatory skin condition causing hives that is often induced by physical or environmental stimuli, is commonly treated with antihistamines, though some patients are refractory. Beyond antihistamines, there is no treatment available globally, explained Edwin Tucker, Jasper’s chief medical officer, so briquilimab has the potential to be “a new treatment paradigm for patients,” both in reducing disease burden and in improving quality of life. Read More
Coins and charts

Akeso raises $250M to expand global pipeline

Akeso Pharmaceuticals Inc. raised $250 million via a public offering that will allow the company to accelerate clinical development of its internally developed drugs in both China and international markets. The offering consists of 31.7 million shares priced at HKD$61.28 (US$7.88) per share and marks the second successful placement in 2024 for Guangdong, China-based Akeso. Following the offering, the company's cash on hand is expected to be $1.064 billion. Read More

Best of BioWorld: Q3

A selection of top news from July through September 2024. Read More

ICYMI: Week in review, Oct. 7-11, 2024

A quick look back at top stories. Read More

Biggest gainers and losers for Oct. 7-11, 2024

The top 10 biopharma stock gainers and losers for the week. Read More

Appointments and advancements for Oct. 14, 2024

New hires and promotions in the biopharma industry, including: Innate. Read More

Financings for Oct. 14, 2024

Biopharmas raising money in public or private financings, including: Hemostemix, Immatics. Read More

In the clinic for Oct. 14, 2024

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Allakos, Cantargia, Capricor. Read More

Other news to note for Oct. 14, 2024

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Eli Lilly, Keybioscience, Turnstone. Read More

Regulatory actions for Oct. 14, 2024

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Dong-A, Genentech. Read More

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