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BioWorld Science

May 3, 1996

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Droxidopa studied in patients with chronic pain

Zambon claims (S)-ibuprofen composition

Phase III data for Quadramet presented at ASCO

Eisai returns sumatriptan rights to Glaxo Wellcome

Xoma, Genentech to collaborate on anti-CD11a

Selectin inhibitor GSC-150 effective in dermatitis models

Merck & Co. patents new cephalosporins

Antibacterial carbapenems from Yamanouchi

Lepetit reports teicoplanin derivatives

New fluoroquinolones from Korean institute

AmBisome launched in Spain

Amphotec efficacy data published

Roche claims stable ganciclovir prodrugs

Cell Pharm to distribute Alferon N Injection in Germany

Sankyo reveals HIV protease inhibitors

Gen-Probe's oligonucleotides inhibit HIV proliferation

UC-70: NNRTI from Uniroyal

Malaria vaccine lead reported by Johns Hopkins

Fujisawa reports collagenase inhibitors

New immunosuppressants from Shionogi

Centeon to codevelop Medarex's MDX-33

HemispheRx, Helix will codevelop nucleic acid compounds

ALT expected to receive streamlined review at FDA

Positive results obtained in AllerVax Cat trial

Antitumor nucleosides disclosed by Yamasa Shoyu

AG-2034 data reported at AACR

Matrix presents improved formulation of vinblastine

Onco TCS slated to enter phase II

MTP-5019 data revealed at AACR

Efficacy data for Gonadimmune reported at AACR

Somatix receives patent coverage for GVAX

Milkhaus to initiate phase I testing of LDI-200 in solid tumors

AG-3340 on track for clinical testing

Sankyo macrophage activators claimed as immunostimulants, antineoplastics

Eisai presents preliminary data on ER-34335

Targretin clinical trials update

NSAID blocks carcinogenesis in rodent models

Receptagen will develop vitamin B12 uptake inhibitors

Somatix receives patent protection for novel glioma treatment

Allovectin-7 clinical results announced at AACR

Vertex dedicates significant efforts to MDR-reversing agents

Hybridon reports oligonucleotide MDR inhibitors

Toray's MIP for treatment of ophthalmological disorders

EPC-K claimed for ophthalmic use

Verteporfin effective in treating severe age-related macular degeneration in early trials

Teijin reports vitamin D3 derivatives for osteoporosis

Ligand, Pfizer settle lawsuit related to osteoporosis drugs

KY-455: Kyoto Pharm.'s ACAT/lipid peroxidation inhibitor

Redux cleared for marketing in U.S.

Progenitor delves into leptin receptor research

DynaGen's lobeline transdermal system receives patent coverage

Novopharm Biotech, BreasTek to codevelop breast cancer monitoring test

FDA approves Biomerica's thyroid disease test

Abbott outlines hepatitis diagnostic research

ProstaScint up for advisory committee review

NDA filing for ViaScint

Asahi discloses anxiolytic/cognition-enhancing drugs

Novel sertraline composition for mood disorders

Anaderm Research formed to develop skin and hair therapeutics

Cadus/Solvay yeast-based drug discovery program receives boost from EC

Drug discovery agreement reached by CombiChem and Teijin

Stealth liposomes possess prolonged stability

Gensia coagulation monitoring system enters phase I

Hafslund Nycomed demerger imminent

Bristol-Myers Squibb opens R&D office in Russia

Sandoz to acquire Imutran

OncoRx gets new identity: Vion Pharmaceuticals

Astrotactin-producing gene may aid in understanding of epilepsy

Pola describes dopamine reuptake inhibitors for Parkinson's disease

Berlex attempts to block approval of Avonex in U.S.

Maxi-K channel modulators from Bayer

RPR describes NMDA/glycine-site antagonists

Jouveinal's neuroprotective sigma ligand JO-1994

Tanabe's T-477 shows neuroprotective effects

TAK-218 discussed at length at Japanese meetings

Ibogaine development to be discussed at international meeting

Rupatadine poised to enter phase II

Arris announces preliminary results for APC-366

Glaxo Wellcome's newest approach to ARDS

Takeda discovers new PGDF inhibitors

More research into angiotensin II antagonists at Takeda

Ajinomoto reports on antihypertensive agent AP-1067

ATP-sensitive K channel opener reported by Chinese academics

Discovery Therapeutics reports on WRC-0571

AHP claims smooth muscle cell proliferation inhibitors for restenosis

TEI-9063 structure linked to new patent

Novel PAI-1 inhibitor protects against vascular lesions

Nasal propranolol claimed by RiboGene for angina Rx

CPC-111 enters phase II for angioplasty indication

Servier develops S-18149 as putative venotropic agent

Fuji Pharm. reports new antiplatelet agent

PS-028: Fibrinogen antagonist from Taisho

Reteplase multiple boluses claimed for thromboembolic conditions

Fujisawa synthesizes novel beta3-agonist

Kureha's new agent for renal disorders

Somatix hepatitis therapy receives patent coverage

Hepagene preliminary phase III results look positive

Plasmin/kallikrein inhibitors from Hisamitsu

Harvard Scientific files IND for impotency treatment

Crinone pivotal study results publicized

Genistein claimed for menopausal and PMS symptoms

Seprafilm approval recommended in U.S.

Testosterone enanthate effective in male contraception study

F-792: Truncated oxytocin analogue from Ferring

HIV protease inhibitors revealed by Warner-Lambert

FR-133605 effective in preclinical models of rheumatoid arthritis, septic shock

Agouron reports phase II data for Thymitaq

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