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BioWorld Science

May 14, 1997

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In vivo profile of AMD-473

Avigen's gene therapy approach shows promise in preclinical studies

Gilead Sciences initiates phase I/II trial of oral PMPA for HIV treatment

In vivo and in vitro characterization of the novel vinca alkaloid F-12158

Endothelin antagonists described by Takeda

New antimigraine agents from Merck Sharp & Dohme

Fibrinogen antagonists reported by Lilly/Cor Therapeutics

Selective alpha1b-adrenoceptor blockers from Merck & Co.

GH secretagogues disclosed by Merck & Co.

Clinical results for titanocene dichloride in solid tumors

Immunex reports new chemokine-binding protein

Clinical results for Zambon's N-acetylcysteine as chemopreventive agent

Lilly synthesizes antifolates that potently inhibit human DHFR

Sugen researchers discover co-crystal of FGF TK

In vivo and clinical antitumor activity of recombinant methioninase

MMP inhibitor from British Biotech effective against oxidant-induced lung injury

Tularik receives U.S. patent relating to enzyme associated with inflammation

Dual H1/NK1 antagonist for allergic rhinitis from HMR

In vivo growth arrest of mammary carcinoma by ibuprofen

Biota licenses compounds for the treatment of prostate cancer

SangStat Medical: Q1 1997 highlights

In vitro effects of combinations of tubulin-interacting agents and S-16020-2

BioChem Pharma subsidiary signs agreement to develop nasally delivered vaccines

Samjin characterizes novel antitumor agent

Promising results reported on new complex carbohydrate antifungal compound

LXR and Oxford Asymmetry enter drug discovery collaboration

AutoImmune reports preliminary results from phase II trials of Colloral

Ilex and LeukoSite form joint venture for development of Campath-1H

RPR and AMRAD initiate collaboration on antiasthmatic natural products

Roche seeks FDA approval for new formulation of saquinavir

Low-dose oral IFN-alpha + high-dose injectable IFN-alpha for hepatitis C

SmithKline Beecham and LG Chemical sign agreement for new antibiotic

CollaGenex promotes Ponstel for short-term dental pain relief

Centocor reports results from Crohn's disease studies