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BioWorld Science

May 11, 1998

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Rasagiline demonstrates neuroprotective effects on dopaminergic neurons

Enzyme inhibitors useful for neurodegenerative disorders prepared at P&U

Initial results in the development of gene therapy for OI reported by NIH

Clotrimazole derivatives in preclinical testing at Imutec

Myriad Genetics awarded fourth patent covering the BRCA1 gene

Ortec's CCS granted humanitarian use device designation

Multikine clinical trials update

Patient enrollment begins for U.S. trial of Maxamine in malignant melanoma

Antithrombotics developed at Proteus available for licensing

Magainin updates status of squalamine program

Comparative studies of L-0066 in animal models of allergic bronchial inflammation

BioFocus and Cubist form antiinfectives alliance

Stockholders approve Intercardia and Transcell merger

Actiq trial results published; NDA amendment filed

Chimeric cytokine receptors for enhancing efficacy of lymphocytes in adoptive immunotherapy

Cubist and Merck & Co. expand antiinfective drug discovery agreement

Roche and Nortran join forces for development of atrial arrhythmia drugs

Isis Pharmaceuticals: Q1 1998 highlights

Cysteine protease inhibitors synthesized at SKB claimed for osteoporosis, arthritis, periodontitis

Compounds for IL-8-mediated diseases in development at SmithKline Beecham

New substituted aromatic compounds for asthma, joint inflammation

BioCryst: Q1 1998 highlights

Compounds for GI tract motility disorders claimed by Yamanouchi

Yamanouchi prepares novel antimuscarinic agents for renal, GI and respiratory disorders

Sankyo reports glycosidase inhibitors in patent literature

Fibrin sealant approved for marketing in U.S.

Invitrogen will market reagents based on Phogen's VP22 technology

Cell Therapeutics plans phase II trials for CT-2584

New chemotherapeutic agent targets sst receptor-expressing cancers

VISX Excimer Laser System approved in Japan

Shaman receives fast track status for Provir

KAA-276, a novel long-acting histamine H1 antagonist for inhalation administration

Dental plaque advisory subcommittee will meet this month

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