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BioWorld Science

Oct. 26, 1998

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New Na+/H+ exchange inhibitors in development at HMR

Nonsteroid progesterone antagonists for cancer, gynecological disorders

Beta-glucuronidase inhibitors as antitumor/antiinflammatory agents

FDA grants fast track status to Surfaxin in MAS

Benzamides with antiulcer, antisecretory and anti-H. pylori effects discovered at Shiseido

Safe and effective therapeutics for neuropathic pain in early development at Roche

In vitro studies point to potent, long-lasting antiplatelet effects for XV-459/DMP-754

Animal studies provide further support for the role of dopaminergic systems in alcoholism

Naamidine A identified as EGF receptor antagonist and antiproliferative agent

Sankyo designs new carbapenems with increased activity, stability to DHP-I

Antibacterial activity of hongoquercin A, a compound of fungal origin

Glycolipid derivative shows cardioprotective activity in animal models

First high-affinity, nonpeptide BB1, BB2 receptor antagonists designed at Parke-Davis

Camptosar receives final FDA approval for colorectal cancer

U.S. patent issues for Regeneron's Ang2 protein

Thalidomide designated orphan drug for multiple myeloma

Clinical trials of Combidex near completion, NDA filing scheduled for next year

Metabasis Therapeutics seeks partner for development of anticonvulsant

Endorex/Elan joint venture to develop Medipad-based drugs

Positive phase II results obtained for Allelix's recombinant hPTH in osteoporosis

Anti-HIV drug candidate DMP-851 reviewed in the literature

Muse effective in patients with ED resulting from radical prostatectomy

New study compares balsalazide to mesalamine

Transdermal D2 agonist therapy with N-0923 safe and effective in PD

STAR study will compare raloxifene to tamoxifen for reducing risk of breast cancer

Transdermal selegiline as monotherapy in mild to moderate Parkinson's disease

Phase I studies establish feasibility, tolerability of oral delivery of heparin

Sublingual apomorphine safe and effective in PD patients with motor fluctuations

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