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BioWorld Science

March 16, 1999

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Novel sublingual apomorphine: efficacy and tolerability in fluctuating Parkinson's disease

Lower mifepristone dose effective as emergency contraception

Biovail's Brexidol receives Canadian marketing approval

Ortho-Clinical Diagnostics and Chiron license HCV antigen test

Synthetic insulin mimetics designed at U. of Virginia

TGF-beta inhibitors for nephritis disclosed by Tsumura

Millennium discovers two novel proteins: Tango-72 and Tango-77

New salt of paroxetine with improved physicochemical characteristics

Peripheral cannabinoid receptor ligands in development at Japan Tobacco

Fujisawa synthesizes hypoglycemic sulfonamides

Hoechst's new MRI contrast agents

New ET receptor antagonist preserves coronary endothelial function in hypercholesterolemic pigs

Structure of Astra's next-generation proton pump inhibitor revealed for the first time

Chinese scientists design antitumor podophyllotoxin derivatives with high selectivity

Licensing opportunity from Yeda: VIP analogues for topical treatment of MED

MMP inhibitor from Pfizer attenuates LV enlargement following MI

Results from major clinical trial on new class of cardiovascular drugs reported at ACC meeting

Corixa's LeIF adjuvant is protected by three new U.S. patents

AstraZeneca merger makes progress with FTC; offer period extended

Xalatan approved in Japan for glaucoma and ocular hypertension

Phase I results with rFGF-2, bFGF in ischemic heart disease

Second prostate cancer study initiated with Multikine

New AZT derivatives with improved anti-HIV activity presented by Hughes Institute

Cardioprotective effects of JTV-519 involve specific activation of PKC isozyme

NeoTherapeutics begins Neotrofin clinical trials in Canada and Australia

Fujisawa decides not to enter Solarase licensing agreement with Hyal

Positive preliminary results from second CholestaGel phase III study

rPSGL-Ig: novel P-selectin antagonist from Genetics Institute as adjunct to thrombolytic therapy

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