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BioWorld Science

April 6, 1999

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Nycomed Amersham: year-end 1998 highlights

Shire: year-end 1998 highlights

Bioniche enters supply agreement with Sanova for Suplasyn

Antisoma's Theragyn granted orphan drug status in the U.S.

Novel furansulfonic acid compounds for neurodegenerative, autoimmune and inflammatory disorders

Roche presents new metabotropic glutamate receptor ligands in the patent literature

Potassium channel modulators for neurological disorders developed at Bristol-Myers Squibb

Noncardiotoxic anthracyclines disclosed by Gem

New anticoagulants/antithrombotics revealed by Zeneca

Potent, selective human beta3-AR agonist characterized by Merck & Co.

Highly potent and selective Y1 receptor antagonists designed at Lilly

Potent, orally active glucagon antagonist developed at Merck & Co.

Ibex implements major changes in new phase III study of Neutralase

Cytel halts clinical trials of Cylexin; company to focus on Epimmune's vaccine programs

Prosorba Column now available in U.S. for treatment of rheumatoid arthritis

Celgene and NCI collaborate on thalidomide cancer trial

FDA approves DepoCyt for treatment of lymphomatous meningitis

Targeted Genetics reports findings of gene therapy trial in cystic fibrosis

Terms of NeuroCell transfer proposal detailed by Genzyme Tissue Repair

Tasosartan provides effective control of essential hypertension in 10-week study

Zeneca files sNDA for change in dosing for Zestril

CAT and Wyeth-Ayerst initiate broad-based target validation and product development collaboration

Regeneron and P&G initiate diabetes-associated obesity trial of Axokine

FDA approval granted for BioTime's blood plasma volume expander

M-Vax cancer vaccine granted orphan drug designation

All rights to INFeD return to Schein

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