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BioWorld - Sunday, March 15, 2026
Home » Newsletters » BioWorld Science

BioWorld Science

April 14, 1999

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BioStratum completes equity financing; updates research goals

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Amarillo begins phase III trial of interferon alfa for Sjogren's syndrome

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Results from phase III study of appendicitis diagnostic reported

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Isis and Elan sign antisense agreement

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Spotlight on MMP inhibitors in development for cancer

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Peptidomimetic inhibitors of cellular Ras protein processing developed at Merck

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Epicyte awarded SBIR and DARPA grants

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Roche describes preparation and use of cell adhesion inhibitors for chronic inflammatory disorders

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Serotonergic agents for depression under study at BASF

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Production method and structure of all-trans-retinol metabolite disclosed by WARF

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Orquest's bone substitute product approved in E.C.

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HMR continues to focus R&D resources in the area of Na+/H+ exchange inhibitors

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Novel macrolide antitumor agent in early clinical trials at Wyeth-Ayerst

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Preclinical studies indicate potential of MMP inhibitor in brain and prostate cancers

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4'-Thio-ara-C selected as potential clinical candidate at Southern Research Institute

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AEterna presents evidence of clinical efficacy of lead MMP inhibitor at AACR meeting

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News from AACR: orally active cemadotin analogue from BASF heads for clinic

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Angiogenic molecules emerge as an important therapeutic target in cancer

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Anti-VEGF aptamer is a potent inhibitor of tumor angiogenesis

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Controlled-release formulation of paclitaxel endowed with superior in vivo antitumor activity

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Once-weekly administration of topoisomerase II inhibitor is associated with reduced toxicity

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Orally active MDR-reversing agent in phase I presented at AACR by Janssen

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NIH investigates next-generation cancer immunotherapeutic

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CL-387785: covalent, irreversible inhibitor of EGF and related receptor tyrosine kinases

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Colazide receives pricing approval in Sweden

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Farnesyltransferase inhibitors especially effective in combination with other chemotherapeutic drugs

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Substituted purines and pyrimidines as inhibitors of cyclin-dependent kinases

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E.U.-wide approval obtained for Regranex

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