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BioWorld Science

April 21, 1999

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Genentech: Q1 1999 highlights

Gene therapy for congestive heart failure studied in mice

Angiotensin immunization as an immunotherapeutic approach to hypertension

Kosan awarded NIH grant for neuroregenerative agent discovery

Thalidomide receives orphan drug status for Crohn's disease

Aastrom launches stem cell therapy technology system in Europe

Neurogen describes novel brain GABA-A receptor ligands

New COX-2-selective agents from Abbott

DuPont patents new series for suppressing CRF hypersecretion and/or treating anxiogenic disorders

Selective inhibitors of VEGF and FGF tyrosine kinase reported by Zeneca

Encore begins phase II trials in prostate cancer patients of its lead product

Telik and Sankyo enter drug screening collaboration

Targretin as novel therapy for refractory breast cancer: preclinical studies

Rodent and early human studies support feasibility of transcutaneous immunization

Cell proliferation induction (CPI): a novel approach to wound healing

Immunomedics clones RNase and prepares RNase-containing anticancer fusion protein

Sonus's EchoGen receives approvable letter from FDA

SQ-885: a specific angiogenesis inhibitor and integrin antagonist

FASEB presentation for PD-159879, an MMP inhibitor with potent antiinflammatory activity

Sanofi and Lilly to jointly develop oxaliplatin in U.S.

FDA advisory committee votes in favor of approval for Vioxx

Vivus receives patent protection for female sexual dysfunction therapy

OVA-IL-18 fusion DNA as a novel immunotherapeutic for asthma

Myriad Pharmaceuticals: new subsidiary to develop lead compounds

Belgian research team designs potent, irreversible and stable DPP IV inhibitors

Hemosol's oxygen carrier cleared for phase III trials in Canada

Novel microbial metabolites activate glucokinase activity

Small peptide from Angstrom highly active against human breast tumor xenografts

Promising results reported at AACR meeting from M-Vax trial in advanced melanoma

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