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BioWorld Science

Nov. 30, 1999

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Phase I clinical trial of Ushercell completed

Company Profile: HepaVec

DWH-146e and rolipram synergistically block inflammation in murine model of peritonitis

Cortecs changes identity to reflect new strategy

Neuronal nicotinic acetylcholine receptor ligands in early development at Pfizer

Anticoagulant, antithrombotic compounds with heterocyclic structure

Helix describes novel antimicrobial therapeutics particularly for Candida and Pseudomonas infections

Sigma-Tau prepares new esters useful as cationic lipids for intracellular (gene) delivery

(Anti)-estrogenic compounds designed at HMR for osteoporosis

GW-395058 assessed for pharmacokinetics and effects on platelets in monkeys

Korean farnesyltransferase inhibitor predicted to have favorable PK profile in humans

IDEC-131: pharmacokinetics and pharmacodynamics in monkeys given repeated infusions

GTI-2501 associated with complete tumor regression in animal models of kidney and breast cancer

First toxicity, pharmacokinetic data for JAK3 inhibitors presented at recent scientific meeting

Therion receives NIH funding for development of novel AIDS vaccines

Ligand applies for E.U. marketing approval of Targretin as CTCL therapy

Sindan and Pfizer team up to develop new multitargeted antifolate

Interneuron licenses U.S. rights to urinary incontinence treatment

Vertex and Taisho collaborate on caspase inhibitor development

3-DP investigators study role of MMP in tumor angiogenesis

Potential lack of drug interactions for the SERMs droloxifene and lasofoxifene

Vanguard to jump on the M&A bandwagon?

Neurocrine Biosciences reports positive phase II results with new insomnia agent

Deracoxib may be suitable for once-daily dosing according to studies in dogs

New lobucavir prodrug and its quantitative determination along with active compound in plasma

Lundbeck and Novo Nordisk join forces to discover innovative drug candidates

FDA approves twice-daily dosing of Viracept

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