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BioWorld - Wednesday, March 11, 2026
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BioWorld Science
March 13, 2000
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Patent covers charged tamoxifen derivatives for cancer therapy
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Kinetek acquires Tyrogene, PTP platforms
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BioQuest and BioKeys sign letter of intent
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Curatek begins pivotal trial of clonidine gel for neuropathic pain
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Liposomal PGE1 to enter phase III trials in critical limb ischemia
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Orphan Medical updates Xyrem development and plans for NDA submission
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AVI BioPharma accelerates development of platform technologies during 1999
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NHLBI stops part of ALLHAT study prematurely, advises against first-line use of alpha-blockers
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Regeneron and Emisphere establish collaboration for oral delivery of Axokine
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The FDA approves Pacis immunotherapy for treatment of bladder cancer
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Phase III trial of Anogesic as treatment for anal fissure pain commences
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Amrad gets the go-ahead to move two new drugs into clinical testing
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Alizyme reports successful completion of phase I trial for IBD therapy
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Malignant melanoma antisense compound enters pivotal trials
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AEterna cleared to commence phase III trial of AE-941 for treatment of kidney cancer
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Connetics files IND for a phase II trial to evaluate ConXn in peripheral vascular disease
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New anti-HIV agents produced by Streptomyces species
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Japanese labs conduct joint research on squalene epoxidase inhibitors
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Distamycin used as lead at P&U to design new alkylating agents
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Suntory's new antiinflammatory agents act as inhibitors of NF-kB
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Shionogi prepares chymase/cytokine inhibitors with beta-lactam structure
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Triazolopyridine antiplatelet agents in the pipeline at Ortho-McNeil
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Enteric-coated methylnaltrexone efficiently prevents GI effects of morphine in humans
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Lipitor receives approval in Japan
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EMLA cream useful as local anesthetic for epidural needle insertion, orotracheal intubation
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Propofol derivative with different behavioral profile: effects on neurotransmitter release
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BMS-193884 safely improves hemodynamics in heart failure patients; data presented to ACC
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Preclinical, clinical studies on Sch-58235 presented at ACC meeting, support further investigations
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