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BioWorld Science

June 16, 2000

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CpG oligodeoxynucleotides for enhancing immune response: NIH offers license

Islet transplantation frees seven diabetes patients from insulin dependence

Neose and Neuronyx to collaborate in neurological disease field

Vernalis consolidates U.K. operations; updates frovatriptan development

ImClone Systems updates Q1 developments

Inex highlights lead product development

AdProTech enters collaboration with PowderJect for DNA vaccine program

Lilly and Emisphere execute development agreement

Antibody agreement signed by Medarex and MedImmune

Enzo Biochem initiates phase II trial for treatment of chronic hepatitis B

Phase I clinical trial begins for Cantab's cervical dysplasia vaccine

IDM signs cancer vaccine agreement with Sanofi-Synthelabo

Cyberonics initiates a pilot study of vagus nerve stimulation in Alzheimer's disease

Cambridge Drug Discovery awarded European grant

Synthetic peptide enhances the microbicidal activity of monocytes

NN-703 derivatives with higher in vivo potency and improved pharmacokinetics

NIP-221, a potent and long-acting thiazolidinedione insulin sensitizer, presented at the ADA meeting

Potent and selective PPARgamma agonist from Nissan shows promise for diabetes Rx

Xeloda approved in New Zealand as treatment for colorectal cancer

ADA news: pregabalin effective and safe in patients with painful diabetic peripheral neuropathy

Polypeptides, polynucleotides with potential in treatment of obesity, etc.

Topiramate reportedly useful in posttraumatic stress disorder

SUNY researchers discover inhibitors of PDC activity, describe use as anticancer agents

Dompe prepares agents for the treatment of neutrophil-dependent pathologies

Ligand's new retinoid RAR antagonists useful for preventing RAR agonist side effects

Novel peptides with thrombopoietic activity disclosed by Amgen in patent literature

Benzoylpyridazines as PDE4 and TNF production inhibitors

Novel PARP inhibitors under study at BASF for various indications

Antiinflammatory substance isolated from coral by U. California researchers

Thrombotic thrombocytopenic purpura associated with clopidogrel

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