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BioWorld Science

Nov. 14, 2000

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PNU-101387G used to link dopamine receptor mechanisms and stress-induced cognitive function

Laboratory studies reveal pharmacological profile of new dopamine D3 receptor antagonist

Activity of new glycylcycline against animal and human bite isolates

Positive phase II results reported for INS-365 as dry eye disease treatment

York Medical acquires Norelin from Biostar

Lead compound designated in Structural Bioinformatics/Yamanouchi collaboration

Telik reports highlights of Q3

SciClone reformulates CPX for CF

UT-15 to be reviewed by FDA advisory committee; promising clinical data reported

Pariet receives E.U. approval for H. pylori eradication in peptic ulcer disease

Novartis extends R&D collaboration with Cubist

Celltech and Cistron Biotechnology complete merger

Abbott submits Biaxin XL sNDA for CAP

Pharmacodynamics of antisense drug ISIS-22023 correlated with concentrations at site of action

AHA news: termination of supraventicular tachycardia by CVT-510

Melagatran dose-dependently reduces platelet and fibrin deposition following angioplasty

New NHE-1 inhibitor with cardioprotective effects in myocardial stunning presented to AHA

Venous and arterial antithrombotic effects described at AHA meeting for DPC-423

Soluble CD39: ex vivo dose-response evaluation in combination with known antiplatelet agents

Fatal cases of hepatotoxicity following Viramune use lead to strengthened drug warnings

Antioxidant BO-653 effective in porcine model of postangioplasty vascular remodeling

New Neurogen compounds modulate blood glucose levels via G-protein-coupled receptors

Brain GABA-A receptor modulators and their use described by Neurogen

Highly effective anti-H. pylori agents designed at Bayer

Recently issued international patent covers Neurogen's novel CRF1 receptor modulators

Synthesis and use of thiazolobenzimidazoles interacting with mglu receptors

Neurotrophic compounds prepared by Krenitsky scientists and their use