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BioWorld Science

Nov. 29, 2000

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Avant Immunotherapeutics to acquire Megan Health

Favorable pharmacokinetic and tolerability profile for Angiozyme in humans

Repligen reports update on product development programs

VX-175 enters series of phase III trials

Dusa moves Levulan into phase I/II for the treatment of acne

TP-10 undergoes phase II evaluation in adult cardiac surgery patients

NicOx's HCT-1026 shows promise for treatment of skin inflammation

Virax's HIV vaccine VIR-201 approved for human study

Company Profile: EpiCept

Acadia succeeds in designing selective 5-HT2A inverse agonists/antagonists based on spiperone

Yamanouchi discovers novel class of potent, nonsteroidal human 5alpha-reductase inhibitors

Phytomedicine continues to show promise for GI inflammatory conditions

Synthetic immunomodulatory peptide inhibits production of proinflammatory cytokines in CD

PK-11195 is able to sensitize cholangiocarcinoma cells to radiation-induced apoptosis

Immediate withdrawal of Lotronex in U.S. announced by Glaxo Wellcome

Amarin licenses U.S. rights to LAX-101 for Huntington's disease

8th UEGW news: alendronate is safe and effective for increasing BMD in Crohn's disease

Fampridine-SR enters phase II trials for MS

Successful completion of Alkermes' first clinical trial with inhaled insulin

Enhanced expression of p21 associated with responses to rAd-p53 gene therapy in NSCLC

Anticoagulants targeting thrombin developed at ADIR

Novel series of cognition enhancers claimed in recent patent by ADIR

Fujisawa synthesizes cyclic hexapeptides with broad-spectrum antifungal activity

Piperidine-based renin inhibitors and their use described by Roche

Integrin alpha4beta1 inhibitors disclosed by AstraZeneca scientists

Tri- and di-aryl acid PPAR modulators claimed by Aventis for diabetes and related disorders

Lyotropic Therapeutics and Elan establish alliance for development of unique drug delivery system

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