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BioWorld Science

March 6, 2001

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Highlights during 2000 at Aradigm

Gemini Genomics to identify genes for depression and anxiety disorders

Xenova and Cantab provide details of merger offer and major products

NeoPharm and NCI expand collaboration for anticancer agent

Abbott acquires BASF's pharmaceutical division

Six-month trial results show Lumigan clinically superior to timolol in lowering IOP

Cell Pathways commences Aptosyn/Taxotere combination phase III trial for NSCLC

Isis and Abbott extend antisense target validation alliance

Results from two phase II trials with INS-1 in PCOS and dyslipidemia

A new class of anthelmintics identified: inhibitors of NADH-fumarate reductase

Bayer investigates seco-cyclothialidine bacterial DNA gyrase inhibitors as antibacterial agents

Broad-spectrum chemokine inhibitor is neuroprotective in rat stroke model

Malaria Vaccine Initiative and GSK to develop pediatric malaria vaccine

Aurora Biosciences and PanVera complete merger

Vivus acquires license to Tanabe Seiyaku's PDE5 inhibitor for ED

Dompe designs small-molecule IL-8 inhibitor with efficacy in animal models of I/R injury

Sustained clinical activity reported in IDEC-114 phase I/II trial for psoriasis

Phase IIa trial results presented at AAD meeting for ABX-IL-8 in psoriasis

AAD news: antipsoriatic activity of low-dose Ontak confirmed in pilot trial

European authorities designate Tracleer an orphan product for pulmonary hypertension

Gene therapy for atherosclerosis based on NOS

New angiopoietin prepared by Bayer may be useful in angiogenesis-related disorders

Peptide GLP-1 and/or exendin-4 agonists identified by Danish pharmaceutical company

New beta-lactamase inhibitors from MethylGene do not require a beta-lactam pharmacophore

Several series of Ortho-McNeil compounds reported to have neurotrophic effects

AstraZeneca claims new chemokine receptor modulators with potential therapeutic use

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