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BioWorld Science

April 20, 2001

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IntraBiotics and Cetek to identify antibacterial and antifungal drug targets

Peregrine's Cotara to enter phase I for treatment of pancreatic and biliary cancer

DSMB safety review of VaxGen's AIDS vaccine favorable

Axcan launches mesalamine suppositories in U.S. for active ulcerative proctitis

Nabi and Acambis establish agreements for use of C. difficile vaccine and i.v. immune globulin

SciClone receives U.S. patent allowance for Zadaxin analogues

ABX-EGF proceeds to phase II trials for kidney cancer

Positive results obtained for HCT-1026 as treatment for contact urticaria

Lexicon Genetics scales up gene knockout program

MGI Pharma highlights Q1 2001 developments

Discovery and characterization of GW-2016, a dual kinase inhibitor, reported at AACR meeting

Utility of dopaminergic stabilizers in neuropsychiatric disorders confirmed with (-)-OSU-6162

Neuroprotective effects of GPI-1046 demonstrated in in vitro and in vivo experiments

FDA Arthritis Advisory Committee meets to review Aslera NDA

Synthetic derivatives of the marine alkaloid meridine endowed with promising antitumor activity

Phase III trial of Metvix PDT indicates superiority to surgery in nodular BCC

NMSO3 as a potential new therapy for rotavirus infections in humans

Demegen to commence clinical trials of oral candidiasis treatment

Medicure successfully completes phase I trial of MC-1; phase II studies planned

Veletri fails to meet primary efficacy objective in RITZ-1

Chinese traditional medicine useful for aplastic anemia

3-D presents newest research on protease inhibitors

Antimycobacterial A-500359 derivatives reported by Sankyo researchers

Cor discloses potent, selective factor Xa inhibitors

Synthesis, activity and use of new inhibitors of lipid peroxidation

Pfizer patents new enzyme inhibitors with utility in lipid disorders, fungal infections, etc.

Japanese patent covers Yamanouchi's VEGF-inhibitory tricyclic heteroaryl compounds

Kyorin dedicates significant resources to the search for PPAR agonists

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