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BioWorld Science

Dec. 27, 2001

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PDL grants license to Celltech for humanized anti-TNF antibodies

Xenon Genetics discovers two new drug targets for metabolic and neurological diseases

Worldwide expansion of Merck/Schering-Plough cholesterol partnership

Asimadoline alters cytokine gene expression in adjuvant arthritis

TAS-108 well tolerated and readily absorbed after oral dosing in preliminary clinical trial

CS-758: a new triazole antifungal agent with promise for candidiasis and aspergillosis

SkyePharma withdraws Solaraze termination notice

Cytovax files for approval to begin human trials of Cytovaxine

Clarinex cleared by FDA for SAR symptom relief, will be launched next month

New option for early-stage prostate cancer receives FDA clearance

Thalomid granted orphan drug status in Europe for multiple myeloma and ENL

Orally active growth hormone secretagogue SM-130686 identified by Sumitomo

Amgen initiates phase III AMG-073 trial for hyperparathyroidism

IL-12 gene therapy studied in Japan for inducing tumor immunity

Phase I trial initiated for antithrombotic drug candidate GH-9001

GSK discontinues development of ADL-2-1294

Potent new MMP inhibitor has excellent oral activity in a rat collagen degradation model

Forest submits NDA for oxycodone/ibuprofen to treat moderate to severe pain

Myriad Genetics seeks clearance for new clinical trial of Flurizan

Companies collaborate in developing neuroprotective compound DD-612

Superior efficacy of triple-antigen hepatitis B vaccine confirmed in inadequate responders

Avigen receives FDA approval to continue clinical trials for Coagulin-B gene therapy

New series from Bayer with excellent antiallergic activity

Lipase inhibitors produced by Streptomyces

CRF antagonists from a series of tricyclic fused pyrimidine and pyridine derivatives

Korean researchers identify new CDK inhibitors

Boston-based scientists disclose radiolabeled tumor imaging agents

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