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BioWorld Science

Feb. 20, 2002

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IL-13 gene therapy improves the course of arthritis in rats

Molecular mechanism of the antiproliferative effect of EGCG revealed

The (R)-(+)-enantiomer of amlodipine is responsible for nitric oxide release

Statin modification of the MAPK pathway in vascular smooth muscle cells

Cardiome shareholders approve acquisition of Paralex

Integrase inhibitors available for licensing from the NIH

Licensing opportunity from NIH: inhibitors of functional dimeric retroviral proteases

NIH offers novel human anti-HIV monoclonal antibody for licensing

Invention related to human cancer-associated gene available for licensing

NIH offers licenses to novel approaches to thyroid cancer therapy

Cholera vaccines offered for licensing by NIH

Combinations of PDE3 and PDE4 inhibitors for autoimmune diseases available from NIH

Preclinical PPARgamma modulators acquired by GSK from Bayer

Merger of Atlantic and Merrimack complete; lead compound expected to enter clinical trials this year

Potential new indication for Gd-Tex emerges from Stanford-based research

AtheroGenics presents review of 2001, looks at year ahead

Hemosol updates Hemolink progress

Initiation of trial of Genasense combination therapy for mantle cell lymphoma

Deltagen completes acquisition of former CombiChem

Remodulin filing accepted, granted priority review in Canada

International collaboration receives grant to test vaginal microbicides

New Lilly Icos compounds effective as PDE5 inhibitors

Cardiovascular therapeutics that mimic the biological actions of pyridoxine and pyridoxal

Synthesis and use of thiophene retinoids in emphysema and associated pulmonary diseases

Yamanouchi discloses compounds for the treatment of sex hormone-related diseases

Cyclic peptides discovered with potential in the treatment of preterm labor

Banyu claims novel series with utility in the treatment of solid tumors

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