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BioWorld Science

April 19, 2002

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LG Chem regains worldwide rights to late-stage quinolone antibiotic

Novel antibacterial agents effective against resistant microorganisms discovered at eXegenics

Antiangiogenic DAC-based peptides presented by ConjuChem

Antimetastatic and antitumor agents targeting uPA system discussed by Wilex at AACR meeting

Maxia research on inhibitors of MKP-1 as potential anticancer agents presented to AACR

Antisense Rad51 inhibitors designed at Pangene for sensitizing tumor cells to DNA damage

Novel class of potent cytotoxic tubulin-interacting agents identified by Zentaris

TNP-470 and docetaxel as combination therapy for transitional cell carcinoma of the bladder

Palonosetron effective for the treatment of chemotherapy-induced nausea and vomiting

Japanese researchers report new preclinical data on the 5alpha-reductase inhibitor TF-505

Isoliquiritigenin shows potential as a prostate cancer preventive

Snapshots of new roles for testosterone in neurological and cardiac disorders

Positive 24-week results from first phase III trial of T-20

Irofulven trial in refractory pancreatic cancer discontinued

Novogen's phenoxodiol stabilizes tumor growth with minimal toxicity

Spiriva approved in E.U. under mutual recognition procedure

NT-13 enhances memory and learning, protects neural tissue and alleviates neuropathic pain

FDA approves Botox Cosmetic for treatment of glabellar lines

Phytopharm completes installation of P-57 manufacturing plant

Novo Nordisk plans to outlicense NN-622

Phase I/II trial of Civacir to prevent HCV reinfection following liver transplant

Endothelin receptor antagonists with utility in hypertension, etc.

Antifungal agents described in patent by Oxford GlycoSciences

Nonabsorbable antibiotics for treatment of gastrointestinal disorders

FT-0554A prepared by Kitasato Institute

Lilly claims agonists of PPARalpha and PPARgamma in recent patent

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