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Home » Newsletters » BioWorld Science

BioWorld Science

June 4, 2002

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Potent dual MMP/TACE inhibitors designed by Novartis

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Kagome presents novel hepatoprotectants

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PDE inhibitors for use in hypertension, etc.

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Piperazine-containing factor Xa inhibitors patented by Cor Therapeutics (Millennium)

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Ajinomoto describes factor Xa-inhibitory benzodiazepines

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New antimalarial compounds designed by Shionogi R&D team

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Schering presents PDE5 inhibitors for erectile dysfunction

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Histamine H3 receptor modulators and their use in sleep disorders, etc.

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Biovail licenses Metformin GR from DepoMed

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Bay-55-9837, a selective VPAC2 agonist, as a potential therapy for type 2 diabetes

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First orally active, selective MCH receptor antagonist identified at Takeda

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Discovery of potent, selective, nonsteroidal GR antagonists using 3-D pharmacophore design

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Cyclophilin-binding compound with immunomodulating, antiasthmatic and antiinflammatory effects

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Gastrointestinal safety of NCX-4016 demonstrated in humans

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Superior GI tolerance of COX-189 compared to naproxen reported in healthy subjects

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Aventis initiates Lovenox trial in patients with acute STEMI

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AltaRex announces major directional change

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Room-temperature Betaseron launched in U.S. for relapsing-remitting MS

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NCX-1015 does not aggravate ischemia/reperfusion-induced gastric injury

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Oryx to market and promote Corvert in Canada

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Advectus collaborates with U. of N. Carolina on brain tumor drug development

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Corixa files request for formal dispute resolution for Bexxar

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Genzyme Transgenics announces name change

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CPMP issues positive opinion for Xigris in severe sepsis

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FDA approves Imagent for ultrasound imaging of the heart

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Known antihypertensive drug shows benefit in normotensive rat model of stroke

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