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BioWorld Science

Oct. 2, 2002

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Novel calcium receptor modulators and their use described in Aventis patent

Two Shionogi patents describe novel immunosuppressant agents

Merck reports development of inhibitors of p38 kinase

Novel cytokine and T-cell production inhibitors and their use in cancer, arthritis, etc.

KN-62 inhibits MAPK/c-Myc activation and proliferation in human keratinocytes

NO-1886 combined with exercise may prevent development of atherosclerosis in the elderly

The antifungal clotrimazole exhibits neuroprotective effects in vitro

PARP inhibitor GPI-6150 effective in rat model of colitis

Antiamnesic effects of DM-232 demonstrated in mice and rats

Efficacy of IS-741 on spontaneous colitis in transgenic rat model

New inhibitors of malonyl-CoA decarboxylase and their use in heart failure, diabetes, obesity, etc.

Vical updates progress of Leuvectin program

Enrollment completed in DIAMOND and SILVER ALT-711 trials

Extended-spectrum oxazolidinone selected for clinical development

INS-37217, a next-generation P2Y2 agonist with an enhanced duration of action

Phase III data in immunocompromised patient population presented for micafungin

Positive results emerge from pilot trial of SCV-07 in tuberculosis

Polyphenon enters pivotal phase III trial for genital warts

Idec gains license to develop HMN-214

IND cleared for Alzhemed phase II

Orphan drug grant for Endostatin trial

Clinical efficacy and safety of ACH-126443 in HBV demonstrated in phase I/II clinical trial

InterMune and Array BioPharma collaborate on hepatitis drug discovery

Twelve-month data show efficacy of anecortave acetate in wet AMD

Iseganan fails to meet primary endpoint in ulcerative oral mucositis phase III trial

deCODE and Merck & Co. form obesity alliance

Triangle's Coviracil outperforms Zerit in phase III trial