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BioWorld Science

June 27, 2003

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Pfizer integrates Pharmacia and reports on pipeline progress

Gemzar/Taxol approved in Finland for metastatic breast cancer

FDA extends Cidecin review period

Enrollment completed in ONTARGET trial of Micardis

DW-1350 inhibits bone resorption and enhances bone formation

Limited antitumor activity for SU-6668 monotherapy in multiple myeloma

Pharmacokinetic data support use of oral deferasirox in transfusional hemosiderosis

Finasteride may reduce the risk of prostate cancer

Good safety and efficacy described for rasburicase in cancer patients with hyperuricemia

Once-daily dosing feasible for canertinib in advanced solid tumors

Lilly patent covers novel orally available LY-354740 prodrugs

Novel IMP dehydrogenase inhibitors under study at Celltech R&D

AstraZeneca presents new ERbeta ligands for AD, anxiety, depression, osteoporosis, etc.

Cyclic peptide with sst receptor-agonist activity identified by SCRAS scientists

Cortex researchers present new AMPA modulators with cognition-enhancing properties

New MMP/aggrecanase inhibitors identified by Pharmacia (Pfizer) team

Merck & Co. describes new MCH1 antagonists, their preparation and use

MethylGene and Merck Frosst enter agreement for antibiotic resistance program

Novartis Ophthalmics obtains development and marketing license for Lucentis

Demegen and Dow form development collaboration

Cytogen signs agreement to reacquire marketing rights to Quadramet

FIT Biotech and IAVI team up to evaluate GTU-MultiHIV for AIDS prevention

Genzyme exercises option to acquire 50% interest in DX-88 for HAE

Preclinical findings for antiangiogenic botanical IDN-5390

Enbrel improves plaque psoriasis symptoms in phase III study

DARPA grant will fund development of CpG TLR9 agonists for use with anthrax vaccine

Good safety and pharmacokinetic profile reported for UR-8880 in healthy volunteers

Combination therapy including bortezomib effective in colorectal cancer model

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