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BioWorld Science

Aug. 29, 2003

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Inhibitors of MraY transferase as potential new antibacterial agents

SSR-591813, a partial alpha4beta2 nAChR agonist, effective in animal models of nicotine dependence

Safety, tolerability and pharmacokinetics of CHF-3381 in healthy volunteers

The neuroprotective agent TV-3326 improves cognitive tasks

Gamma-tocotrienol: a natural vitamin E homologue with natriuretic function

New gene therapy platform to treat focal seizure disorders

Topical TMC-120, a NNRTI, inhibits vaginal transmission of HIV-1 in hu-SCID mice

In vitro anti-HIV-1 activity of leflunomide reported by U. of Zurich researchers

AM-1241 reverses neuropathic pain in rats via activation of CB2 receptors

Potent activities of 1beta-methylcarbapenems against multiresistant Gram-positive bacteria

A new 5-HT2A receptor antagonist with high selectivity and potent efficacy

Expert guidelines established for the management of postoperative nausea and vomiting

ATL-1102 enters phase I trial for MS

BMS and Flamel enter Basulin agreement

Orphan drug designation for glioma drug 131I-TM-601

BioCryst ends collaboration with 3-Dimensional Pharmaceuticals

Another series of herpesvirus DNA polymerase inhibitors presented by Pharmacia

Novel chemokine CCR4 receptor modulators and their use in asthma therapy

Arena patent covers 5-HT2A receptor modulators for psychosis, platelet aggregation, asthma, etc.

New tyrosine kinase inhibitors in early development at Novartis

Indian researchers describe new triazole-based antibacterial agents

Novel p56lck inhibitors described with potent activity against T-cell proliferation

Procter & Gamble claims CRF2 agonists with utility in muscular dystrophy

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