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BioWorld Science

Sep. 17, 2003

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PDGF-D: a novel target for the treatment of mesangioproliferative glomerulonephritis

TV-3326 attenuates MPTP-induced dopaminergic neurotoxicity in mice

CHF-3381 blocks NMDA receptors in vitro and in vivo

BN-82451 attenuates striatal lesions in a rat model of Huntington's disease

ETA receptor antagonism preserves myocardial perfusion response in hypercholesterolemic pigs

New JNK3 and/or hCK1e inhibitors from fungal origin claimed by Aventis

Roche and Vernalis present novel 5-HT2C agonists for obesity and other uses

Novel LXR modulators discovered by Tularik team

Vicore patent covers new AT2 agonists and their use in dyspepsia, IBS, etc.

King patents adenosine A2B antagonists with utility in asthma and ocular disorders

New antithrombotic serine protease inhibitor patented by former Pharmacia

Nexium intravenous formulation submitted to FDA

DOS-47 demonstrates preclinical antitumor activity

Bicifadine as effective as tramadol in phase III pain study

InNexus and Corixa enter antibody research, development and license agreement

New trial approved to evaluate GTI-2040 in combination with docetaxel for NSCLC

Efficacy of drug for dry mouth in preventing lung cancer claimed in recent patent

New option for patients with lipid disorders introduced in U.S.

Anti-invasins as a novel class of antifungal agent

Merck and Alnylam enter RNAi development collaboration

Valcyte approved for CMV prevention in transplant patients

New multiple-dose trial evaluates R-112 for allergic rhinitis

Panacea expands research agreement with MIT

BresaGen acquires XeriJect drug delivery platform

Fungicidal compound GL-48656 possesses favorable in vivo properties

Acylides synthesized at Taisho to overcome resistance in key respiratory tract pathogen

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