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BioWorld Science

Nov. 11, 2003

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A high dose of ximelagatran better than warfarin in preventing DVT after total knee replacement

Cognitive and functional improvements associated with donepezil in vascular dementia

Improved quality of life seen in SLE patients treated with LJP-394

Good cardiovascular safety profile described for ospemifene in postmenopausal women

New inhibitors of VLA-4-mediated cell adhesion developed at Toray

Durable antiviral response induced by tipranavir in heavily pretreated HIV patients

Antiviral activity and pharmacokinetics of SPD-754 in HIV infection

Novel histamine H1 antagonists under study at Almirall Prodesfarma

Pfizer patent covers new NS5B inhibitors with potential in HCV infection

BMS researchers present new protein kinase inhibitors for proliferative and inflammatory disorders

New ErbB kinase inhibitors, their preparation and use revealed in AstraZeneca patent

Ajinomoto presents novel benzodiazepine-based factor Xa inhibitors

Banyu team identifies new glucokinase activators

Indian scientists claim new antibacterial oxazolidinones in recent patent

CAP delivery system extends duration of insulin action in preclinical study

Lysostaphin eradicates MRSA biofilms on artificial surfaces

Hybrigenics and Servier sign new drug discovery agreements

Lexicon moves into ophthalmology

Maxim seeks European approval for Ceplene treatment

Enrollment under way for phase IIb obesity study of AOD-9604

Chiron grants Vertex HCV license

Phase I trial commences for Oxycyte

Specific VRAC inhibitor with antiarrhythmic effects presented in Orlando

Inhibition of malonyl-CoA decarboxylase modulates fatty acid oxidation in rat hearts

LXR agonist ATI-829 increases brain apo E in vitro and in vivo

AR-10A exhibits a suitable profile for further development as an antiobesity agent

JNJ-17153656, a dual delta/mu opioid receptor agonist for GI disorders

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